research Fibre optic confocal imaging (FOCI) of keratinocytes, blood vessels and nerves in hairless mouse skin in vivo
Fibre optic confocal imaging can visualize skin layers, blood vessels, and nerves in live mice.
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270-300 / 1000+ resultsresearch Plasticity of GABAergic Inhibition
Targeting specific GABA receptors may help treat epilepsy and postpartum depression.
research Genes and Immune Response in Alopecia Areata: Review of the Alopecia Areata Research Summit First Day Proceedings
Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.
research Polymeric Nanohydrogel in Topical Drug Delivery System
Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.
research Chemistry42: An AI-Driven Platform for Molecular Design and Optimization
Chemistry42 effectively creates and optimizes new molecules for drug discovery.
research Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis
Bioengineered skin models help reduce animal testing and advance research in cosmetics and skin disease.
research A Review of the Characteristics of Clinical Trials and Potential Medications for Alcohol Dependence: Data Analysis from ClinicalTrials.gov
No medications for alcohol dependence have been approved for marketing yet.
research Integrative Nutritional Mechanisms of Keyora Lycopene 23 in 1 Man's Multi-Vitamin in Erectile Dysfunction, Male Infertility, Prostatic Disorders, and Metabolic Dysregulation
Keyora Lycopene 23 in 1 multi-vitamin improves men's reproductive and metabolic health.
research Keyora Integrated Nutritional Modulation of the Redox–NO–Androgen Axis in Male Endocrine, Reproductive, and Metabolic Disorders
Nutritional interventions can help restore balance in male health by targeting oxidative stress and hormonal issues.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research A study to assess the co-morbidities and complications of polycystic ovarian syndrome
The study found that heart disease is common in people with PCOS and that being overweight is a major risk factor; lifestyle changes and medication are important for management.
research Hair-Pulling Disorder
New treatments for hair-pulling disorder focus on personalized approaches and combining therapies for better results.
research Recent Advances in Wound Healing, Tissue Repair, Regeneration and Scar Management
New therapies and personalized approaches improve wound healing and patient quality of life.
research Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling
FGF18 helps keep hair in its resting phase, affecting hair growth cycles.
research Edar Signaling in the Control of Hair Follicle Development
Edar signaling is crucial for proper hair follicle development and function.
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research International evidence‐based guideline on assessment and management of PCOS —A Nordic perspective
The guideline refines PCOS diagnosis, promotes a healthy lifestyle, reviews treatments, and stresses long-term follow-up.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Unmasking the Overlooked Symptoms of PCOS: Navigating Ovulatory Dysfunction, Menstrual Disorders, and Acne
PCOS requires personalized treatment to manage symptoms and improve fertility and quality of life.
research The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
research Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.
research Signal integrator function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research The latest reports on androgenetic alopecia
New treatments for common hair loss are needed.
research An overview of current strategies and future prospects in drug repurposing in tuberculosis
Drug repurposing offers promising strategies to improve tuberculosis treatment despite challenges.
research Exploring links between acne and metabolic syndrome: a narrative review
Acne may signal underlying metabolic issues, and lifestyle changes can help manage both.
research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions
One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.
research Drug repurposing—a promising approach for patients with angina but non-obstructive coronary artery disease (ANOCA)
Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
research Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research The Potential of Ginkgo biloba as a Source of Biologically Active Compounds—A Review of the Recent Literature and Patents
Ginkgo biloba has health benefits but also contains toxic compounds, driving interest in its use in medicine and food.