12 citations
,
July 2020 in “Aging” The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.
1036 citations
,
August 2019 in “Cells” Mesenchymal stem cells can help repair body tissues with low risk of rejection.
41 citations
,
October 2019 in “Biomolecules” Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.
30 citations
,
May 2019 in “Medicinal Research Reviews” Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
3 citations
,
April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
19 citations
,
May 2018 in “Molecular Medicine Reports” miR‑339‑5p can slow down hair follicle stem cell differentiation by targeting DLX5.
2 citations
,
June 2022 in “International Journal of Molecular Sciences” Lower levels of certain genes in hair cells improve hair loss treatment outcomes.
1 citations
,
September 2023 in “Stem cell research & therapy” Mesenchymal stem cells could help treat aging-related diseases better than current methods.
25 citations
,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
21 citations
,
August 2024 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.
15 citations
,
December 2020 in “International journal of molecular sciences” Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
9 citations
,
September 2022 in “Journal of Clinical Investigation” Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
19 citations
,
August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
1 citations
,
October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
January 2025 in “Antioxidants” SHED-CM can reduce hair graying and protect against damage from X-rays.
January 2022 in “Stem cell biology and regenerative medicine” iPSCs could help develop treatments for hair loss.
283 citations
,
February 2011 in “Cell stem cell” COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.
September 2025 in “Frontiers in Cell and Developmental Biology” Retinoic acid may help heal skin without scars by reducing fibrosis and supporting skin regeneration.
January 2025 in “Frontiers in Cell and Developmental Biology” Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
425 citations
,
June 2020 in “Nature” Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
87 citations
,
March 2015 in “The EMBO Journal” Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.
17 citations
,
May 2021 in “Journal of Cell Science” N1-acetylspermidine promotes hair follicle stem cell self-renewal.
12 citations
,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
36 citations
,
January 2021 in “Frontiers in Cell and Developmental Biology” Hypoxia and epigenetics are crucial for cell growth and tissue regeneration.
1 citations
,
June 2024 in “Preprints.org” Dermal sheath cells play a key role in wound healing and could impact fibrosis.
July 2025 in “Genome biology” HT-scCAT-seq helps understand gene regulation in embryonic skin development.
105 citations
,
December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.