research Neurosteroids in Adult Hippocampus of Male and Female Rodents: Biosynthesis and Actions of Sex Steroids
Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.
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960-990 / 1000+ resultsresearch Pubertal hormones increase hippocampal expression of α4βδ GABAA receptors
Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
research Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework
A new method effectively predicts estrogen-related health effects for early screening.
research The interaction between finasteride and corticosterone levels: implications for depression-, and anxiety-like behavior and hippocampal synaptic plasticity in male rats
Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.
research Environmental Exposures and Reproductive Health
Environmental and social factors greatly affect women's reproductive health.
research Addisonian crisis in a young man with atypical anorexia nervosa
A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.
research Screening for associated autoimmune disorders in Polish patients with Addison’s disease
research Introduction to: Endocrinological aspects of andrology—what is new?
The document discusses new insights into how hormones affect male sexual health and related conditions.
research Hepatic and renal impairment and degenerative changes caused by carbon black nanoparticles in mice
Carbon black nanoparticles can harm liver and kidney function in mice.
research Identification of key genes in type 2 diabetes‐induced erectile dysfunction rats with stem cell therapy through high‐throughput sequencing and bioinformatic analysis
Stem cell therapy affects 15 key genes in rats with diabetes-related erectile dysfunction.
research Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in the Screening
The case emphasizes the need for careful screening in children for insulin resistance and related conditions.
research Type 1 interferon signature and cytotoxic T lymphocyte activation targeted against sweat ducts in inflammatory acquired idiopathic generalized anhidrosis
Inflammation damages sweat ducts, causing sweat gland injury.
research Persistent adverse effects of antidepressants
Antidepressants can cause long-term side effects like severe withdrawal symptoms and sexual dysfunction, which can last for months or years after stopping the medication.
research Schimmelpenning Syndrome: A Neuro-Oculo-Cutaneous Disorder
Schimmelpenning Syndrome requires careful evaluation and tailored treatment for skin, eye, and developmental issues.
research Familial Cortisol Resistance: Differential Diagnostic and Therapeutic Aspects
The woman had a genetic condition causing high cortisol and androgen levels, treatable with dexamethasone.
research Regard the end: Harnessing physiology to provide better understanding of the mechanisms underpinning frailty
Understanding how different body systems interact can improve how we prevent or treat frailty in aging.
research Changes in Progesterone Metabolites in the Hippocampus Can Modulate Open Field and Forced Swim Test Behavior of Proestrous Rats
Lowering 3α,5α-THP in the hippocampus increases anxiety and depression in proestrous rats.
research Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice
Overexpressing noggin in mice causes severe osteoporosis.
research Effective holistic characterization of small molecule effects using heterogeneous biological networks
Integrating biological networks improves drug repurposing and ADR prediction.
research Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin
The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
research The Neurobiology of Sexual Function
Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
research Acquired 11β-hydroxylase Deficiency by Inhaled Etomidate and its Analogues: A Mimic of Congenital Adrenal Hyperplasia
Inhaled substances in e-cigarettes can cause hormone imbalances similar to congenital adrenal hyperplasia.
research Neutrophil extracellular traps impair regeneration
Neutrophil extracellular traps slow down hair follicle healing after injury.
research Rapid nongenomic modulation by neurosteroids of dendritic spines in the hippocampus: Androgen, oestrogen and corticosteroid
Sex and stress steroids quickly change brain cell structures in the hippocampus.
research Severe metabolic disorders coexisting with Werner syndrome: a case report
A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.
research Analysis of hidradenitis suppurativa–linked mutations in four genes and the effects of PSEN1-P242LfsX11 on cytokine and chemokine expression in macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research Androgen‐induced neurite outgrowth is mediated by neuritin in motor neurones
Androgens help motor neurons grow by increasing neuritin.
research 8679 Case: The Sexual, Physical and Psychological Effects of Post-Finasteride Syndrome
Post-finasteride syndrome can cause lasting sexual, physical, and mental health issues with limited treatment options.
research Ovarian Cycle‐Related Neurosteroid Regulation of GABA‐A Receptor Subunit Plasticity in the Hippocampus Subfields
Progesterone-derived neurosteroids affect GABA-A receptor expression, influencing epilepsy during menstrual cycles.
research Endocrinology of Hirsutism: From Androgens to Androgen Excess Disorders
The book explains how excess male hormones can affect various conditions like Polycystic Ovary Syndrome and Cushing's disease.