research Toll-like receptor 4 (TLR4): new insight immune and aging
TLR4 is important in aging-related diseases and could be a new treatment target.
Search
for
Sort by
Research
600-630 / 1000+ results research Identificación de la variación molecular y genética subyacente a las enfermedades de la piel
Non-coding RNAs may be key in diagnosing and treating rare skin disorders.
research Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants
The document suggests doctors should watch for bone marrow suppression and severe hair loss in patients treated with Azathioprine.
research Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia
Natural killer and CD8+ T cells play a key role in hair loss in androgenetic alopecia.
research Halo naevi, vitiligo and diffuse alopecia areata associated with tocilizumab therapy
Tocilizumab therapy may cause skin and hair conditions like halo naevi, vitiligo, and alopecia areata.
research Generation of autoreactive CD8 T cell in a mouse model of alopecia areata
Alopecia areata involves unique activation of certain immune cells.
research Experimental Models and Molecular Pathogenesis: An Integrated Review of Alopecia
Current models for studying alopecia are inadequate, and more human-like systems are needed.
research 586 Increase in CD8+ effector memory cells re-expressing CD45RA (TEMRA) reflects disease activity and enables early prediction of therapeutic outcome in rapidly progressive alopecia areata
Increased TEMRA cells can predict treatment outcomes in rapidly progressive alopecia areata.
research OXYTOCIN RECEPTOR EXPRESSION IN HAIR FOLLICLE STEM CELLS: A PROMISING MODEL FOR BIOLOGICAL AND THERAPEUTIC DISCOVERY IN NEUROPSYCHIATRIC DISORDERS
Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.
research Immune niches for hair follicle development and homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research Thinking a little differently: A member reflects on life as a neurodivergent physiologist
A neurodivergent physiologist reflects on how his unique perspective benefits his research, despite facing challenges with tasks and communication.
research Effective holistic characterization of small molecule effects using heterogeneous biological networks
Integrating biological networks improves drug repurposing and ADR prediction.
research Therapeutic update on alopecia areata: a critical review of standard and emerging targeted therapies
research Knismesis: the aversive facet of tickle
Light tickling can be unpleasant and may feel worse for individuals with autism.
research Low-Dose IL-2 for Treating Moderate to Severe Alopecia Areata: A 52-Week Multicenter Prospective Placebo-Controlled Study Assessing its Impact on T Regulatory Cell and NK Cell Populations
The study's results on the effectiveness of low-dose IL-2 for alopecia areata and its impact on immune cells were not provided.
research Hair follicle is a target of stress hormone and autoimmune reactions
Stress hormones and autoimmune reactions can cause hair loss.
research IMMUNOLOGICAL AND SOME BIOLOGICAL BIOMARKERS INVESTIGATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Immune-Molecular Link between Thyroid and Skin Autoimmune Diseases: A Narrative Review
Thyroid and skin autoimmune diseases share genetic and immune links, affecting both tissues.
research Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
research Efectos de la alteración de los niveles de allopregnanolona durante periodos críticos del neurodesarrollo en la vulnerabilidad al consumo de alcohol
Early NAS level changes affect alcohol consumption vulnerability.
research Great Expectations: Induced pluripotent stem cell technologies in neurodevelopmental impairments
iPSCs help understand and treat neurodevelopmental disorders.
research Comparative evaluation of cytokine profiles in pediatric alopecia areata patients considering concomitant atopic diseases: An observational cohort cross-sectional study
Personalized treatment considering atopic status and cytokine profiles may help in managing pediatric alopecia areata.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Neurosteroids as Endogenous Regulators of Seizure Susceptibility
Stress increases neurosteroids that help prevent seizures.
research Local Changes in Neurosteroid Levels in the Substantia Nigra Reticulata and the Ventral Tegmental Area Alter Chronic Ethanol Withdrawal Severity in Male Withdrawal Seizure‐Prone Mice
Ethanol withdrawal reduces the brain's response to certain calming steroids, making seizures harder to control.
research GENETIC CONTROL OF CYTOKINES
Genes affect cytokine production, which can influence chronic diseases, and certain interventions may help prevent related molecular damage.
research Live imaging of skin immunity using two-photon microscopy: a short review
Two-photon microscopy improves skin imaging but faces safety and cost challenges for clinical use.
research Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery
Pregnancy-related hormone changes affect Y1 receptor gene expression in mice.
research CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17
CXCL12+ fibroblasts help recruit neutrophils to fight skin infections.
research Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation
Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.