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February 2022 in “The journal of neuroscience/The Journal of neuroscience” Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
miR-214-3p helps nerve repair and recovery.
Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.
A new microneedle patch helps repair spinal cord injuries by reducing scarring and promoting nerve growth.
25 citations
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June 2017 in “Scientific reports” Stress worsens Tourette symptoms by increasing allopregnanolone levels.
Sphingosine 1-phosphate helps control mechanical pain.
42 citations
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March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
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January 2024 in “Theranostics” Intranasal delivery of gene therapy shows promise for treating ischemic stroke.
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October 2014 in “Annual Review of Pharmacology and Toxicology” Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
Onabotulinum toxin A may help treat trichotillomania and promote hair growth.
29 citations
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March 2022 in “Biomedicines” Enhancing antioxidant responses can improve treatments for various diseases.
January 2022 in “International review of movement disorders” Cannabinoid and steroid-based drugs could be new treatments for Tourette syndrome, but more research is needed to confirm their effectiveness and safety.
September 2013 in “Science” The document concludes that human astrocytes aid stroke recovery, research confidence affects student career aspirations, collagen affects cancer spread, a microRNA suppresses brain cancer growth, calmodulin regulates water channels, and small magnesium pieces deform differently.
April 2016 in “Journal of Investigative Dermatology” Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.
January 2024 in “Wiadomości Lekarskie” New methods are being developed to improve drug delivery to the brain.
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.
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December 2009 in “Journal of the Peripheral Nervous System” TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.
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November 1991 in “Brain Research” Aδ-LTMRs have complex synapses with glycine, while Aβ-LTMRs have simpler ones.
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
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September 2017 in “Hormones and behavior” δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Restoring cell communication can treat tissue disorders.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Restoring cell communication can treat tissue disorders.
Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.
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February 2025 in “GeroScience” Increasing neuropeptide Y in the brain can slow aging signs in mice.
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January 2022 in “Frontiers in Neurology” Effective pain management in multiple sclerosis requires individualized treatment strategies.
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September 2011 in “Pain” PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.
miR-214-3p helps nerve repair and recovery.
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April 2009 in “Journal of Neuroscience Research” HDAC inhibitors help brain cells grow and improve brain function.
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August 2014 in “PLoS ONE” GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.