research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
Skin-derived precursors in hair follicles come from different origins but function similarly.
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research Local synthesis and function of neuro-estrogen and neuro-androgen: impact on the hippocampus-related cognition and neuronal plasticity
Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.
research Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Retardation of Hair Follicle Development by the Deletion of TrkC, High-Affinity Neurotrophin-3 Receptor
Lack of TrkC receptor delays hair follicle development.
research Combination of media, biomaterials and extracellular matrix proteins to enhance the differentiation of neural stem/precursor cells into neurons
Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
research Embryonic development of hair follicle pluripotent stem (hfPS) cells
research Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration
Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
research Nociceptive and Nonnociceptive Roles of TRPV3 and Its “Druggability”
TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
research Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin
Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Melatonin membrane receptors in peripheral tissues: Distribution and functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research New developments in our understanding of acne pathogenesis and treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Dermal fibroblast in cutaneous development and healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
research SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair
SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
research RANK as a therapeutic target in cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
research Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research The cellular basis of mechanosensory Merkel-cell innervation during development
BMP signaling is essential for the development of touch domes.
research Skin-type-dependent development of murine mechanosensory neurons
Mechanosensory neurons adapt to different skin types after birth.
research Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research Melatonin induces a stimulatory action on the scrotal skin components of Soay ram in the non-breeding season
Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.
research Different Requirements for GFRα2-Signaling in Three Populations of Cutaneous Sensory Neurons
GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
research Gene-knockout mice with abnormal epidermal and hair follicular development
Knocking out certain genes in mice helps understand skin and hair growth problems.
research Current Development of Mesenchymal Stem Cell-Derived Extracellular Vesicles
MSC-derived EVs show promise for therapy, but production and understanding need improvement.
research Biology of melanocytes in mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research Directing Rat Hair Follicle Stem Cells Toward Neuronal Lineage With Enhanced Trophic Factor Expression
Chick embryo extract helps rat hair follicle stem cells become more like neurons.
research Hair follicle stem cells promote epidermal regeneration under expanded condition
Hair follicle stem cells help skin heal and grow during stretching.
research Proteins observed in scalp hair from preschool children
Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.