55 citations
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June 2014 in “Nature Communications” Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
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January 2007 in “Climacteric” Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
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October 2023 in “Oncogene” p63 is essential for controlling epithelial stem cells and tissue health.
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November 2001 in “Urology” The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
53 citations
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September 2020 in “Stem Cell Research & Therapy” New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
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July 2009 in “Journal of the American Academy of Dermatology” The study suggests smoking is common in HS patients but its role is unclear, and more research is needed to understand HS causes.
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June 2021 in “Signal Transduction and Targeted Therapy” The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
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September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
51 citations
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March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
51 citations
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November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
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March 2021 in “Journal of investigational allergology & clinical immunology” Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
50 citations
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May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
50 citations
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January 2016 in “The FEBS journal” RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
50 citations
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February 2007 in “Expert Opinion on Biological Therapy” Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.
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November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
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July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
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January 2018 in “Scientific Reports” Hair analysis can reveal metabolic changes and potential pregnancy complications.
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September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
48 citations
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January 2017 in “Skin Pharmacology and Physiology” Finasteride-loaded nanoparticles may help treat alopecia.
48 citations
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May 2015 in “NPJ microgravity” A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
48 citations
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June 2014 in “Neurobiology of Disease” The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
48 citations
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July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
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March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
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June 2011 in “Movement Disorders” The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
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November 2002 in “Journal of Neurochemistry” Progesterone boosts alcohol's effect on brain, finasteride counters it.
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
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June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
46 citations
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September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
46 citations
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October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.