Search

for
Search:

Sort by

Research

30 / 1000+ results

research Refractory Trichodynia Treated Using Onabotulinumtoxin-A

8 citations , March 2020 in “Pain Medicine”

This case report described a 25-year-old female with refractory trichodynia, a condition characterized by scalp pain and discomfort, potentially linked to hair loss. Traditional treatments, including pregabalin, amitriptyline, and propranolol, were ineffective. The patient was treated with off-label onabotulinumtoxin-A (BoNT-A) injections, which led to significant improvement and eventual resolution of symptoms after three treatment cycles over nine months. The study suggested that BoNT-A could modulate pain by inhibiting neuropeptide release, offering a potential new treatment for trichodynia, especially in cases unresponsive to conventional therapies. Further research was recommended to explore BoNT-A's efficacy in larger patient populations and its potential impact on hair loss associated with trichodynia.

research A neuroendocrinological perspective on human hair follicle pigmentation

56 citations , November 2010 in “Pigment Cell & Melanoma Research”

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

research New approach to the understanding of keloid: psychoneuroimmune–endocrine aspects

21 citations , February 2015 in “Clinical Cosmetic and Investigational Dermatology”

Keloids may be influenced by stress and psychological factors.

research Gene polymorphisms and serum levels of BDNF and CRH in vitiligo patients

July 2022 in “PLOS ONE”

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

research Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?

26 citations , May 2014 in “BioEssays”

Using neurohormones to control keratin can lead to new skin disease treatments.

research Cutaneous neuroimmunology – lessons from the hair follicle

September 2004 in “Experimental Dermatology”

Stress and certain chemicals affect hair growth by interacting with the immune and nervous systems.

research Neuroendocrine Controls of Keratin Expression in Human Skin

December 2018 in “IntechOpen eBooks”

Neurohormones help control skin health and could treat skin disorders.

New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

research New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP₃‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75^NTRand TrkA) inex vivohuman male androgenetic scalp hair follicles

12 citations , April 2020 in “British Journal of Dermatology”

Caffeine may help reduce stress-induced hair loss.

A Novel Link Between Human Hair Follicle Neuroimmunology and Mitochondrial Biology: Substance P Increases Intrafollicular Oxidative Stress and Mitochondrial Biogenesis

research LB1017 A novel link between human hair follicle neuroimmunology and mitochondrial biology: Substance P increases intrafollicular oxidative stress and mitochondrial biogenesis

July 2022 in “Journal of Investigative Dermatology”

Substance P may contribute to hair loss by increasing oxidative stress and mitochondrial activity in hair follicles.

research Stress and the Hair Follicle

61 citations , March 2003 in “American Journal Of Pathology”

Stress can cause hair loss and skin issues by affecting hair growth cycles.

research Stress, Hair Growth Control, and the Neuro-Endocrine-Immune Connection

7 citations , October 2000 in “Allergo Journal”

Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.

research Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways

3 citations , July 2023 in “International journal of molecular sciences”

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

research Hair melanocytes as neuro-endocrine sensors—Pigments for our imagination

43 citations , October 2005 in “Molecular and cellular endocrinology”

Hair melanocytes help the skin respond to stress and regulate hair pigmentation.

Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

36 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

research Single cell deciphering of pruritic keloids: the interaction between fibroblasts and Schwann cells through the Midkine signaling

1 citations , January 2025 in “Burns & Trauma”

Targeting Midkine can help reduce pain and itching in keloids.

research Neuroimmunomodulation in chronic wounds: an opinion

March 2025 in “Frontiers in Cell and Developmental Biology”

Improving nerve and immune interactions may help heal chronic wounds.

research Wound healing

January 2012

Wound healing is complex and requires more research to enhance treatment methods.

research Neurogenic skin inflammation in stress‐triggered inhibition of hair growth in mice is promoted via nerve growth factor‐dependent pathways

September 2004 in “Experimental Dermatology”

Stress increases nerve growth factor, causing hair loss in mice.

research Complex Regional Pain Syndrome Type I : measurements and treatment

January 2004

CRPS I is complex, linked to immune and nerve issues, and needs comprehensive treatment.

Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control

research Thyrotropin releasing hormone (TRH): a new player in human hair‐growth control

72 citations , October 2009 in “The FASEB journal”

TRH stimulates human hair growth and extends the hair growth phase.

research Is thyrotropin-releasing hormone a novel neuroendocrine modulator of keratin expression in human skin?

10 citations , February 2013 in “British Journal of Dermatology”

Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.

Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways

66 citations , July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Thyrotropin-Releasing Hormone Promotes Wound Re-Epithelialisation in Frog and Human Skin

research Thyrotropin-Releasing Hormone (TRH) Promotes Wound Re-Epithelialisation in Frog and Human Skin

46 citations , September 2013 in “PLOS ONE”

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

Restoring Neuropeptide Y Levels In The Hypothalamus Ameliorates Premature Aging Phenotype In Mice

research Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice

4 citations , February 2025 in “GeroScience”

Increasing neuropeptide Y in the brain can slow aging signs in mice.

Neonatal Finasteride Administration Decreases Dopamine Release in Nucleus Accumbens After Alcohol and Food Presentation in Adult Male Rats

research Neonatal finasteride administration decreases dopamine release in nucleus accumbens after alcohol and food presentation in adult male rats

3 citations , May 2016 in “Behavioural Brain Research”

Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.

Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists

November 2015 in “Journal of the Korea Academia-Industrial cooperation Society”

The new assay can help develop products for hair re-growth.

research Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes

284 citations , May 2002 in “Proceedings of the National Academy of Sciences”

CRH promotes fat production in skin cells, affecting conditions like acne.

research Neuropeptídeos na pele

27 citations , August 2003 in “Anais Brasileiros de Dermatologia”

Neuropeptides affect skin inflammation, repair, and hair growth, with potential for therapy.

research Burden of Hair Loss: Stress and the Underestimated Psychosocial Impact of Telogen Effluvium and Androgenetic Alopecia

162 citations , August 2004 in “Journal of Investigative Dermatology”

Hair loss causes stress and affects mental health; treatment and support needed.