September 2022 in “Translational Andrology and Urology” Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
23 citations
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October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
October 2025 in “Actualización en Medicina de Familia” New drugs face challenges due to limited evidence, and safety updates are advised for some existing medications.
1 citations
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May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.
18 citations
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January 2009 in “Acta neurologica Scandinavica” Long-term sodium valproate treatment for epilepsy generally caused mild and temporary side effects.
September 2024 in “Frontiers in Neuroendocrinology” 5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
December 2025 in “International Neurourology Journal” Alpha-blockers and 5-alpha reductase inhibitors don't significantly increase dementia risk.
January 2022 in “Indian Journal of Psychiatry/Indian journal of psychiatry” Lithium for bipolar disorder can cause skin problems like rashes, which go away when the medication is stopped.
7 citations
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October 2020 in “Dermatology practical & conceptual” Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.
17 citations
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January 2020 in “The World Journal of Men's Health” Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
3 citations
,
October 1976 in “BMJ” Sodium valproate can cause low platelets and hair loss.
December 2025 in “Instituto Politécnico do Porto” Patients with mood disorders using 5α-reductase inhibitors may have a higher risk of suicidal thoughts.
2 citations
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March 1976 in “PubMed” Neogynon effectively prevents pregnancy but may cause side effects like headaches and menstrual changes.
January 2024 in “Pharmaceutical medicine” Most European physicians know the risks and safe use of Cyproterone acetate, but few remember receiving official safety communications.
11 citations
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January 1980 in “PubMed” Oral contraceptives can cause nausea, headaches, mood changes, and other side effects, especially early on.
October 2025 in “Dermatology and Therapy” Adults with alopecia areata have a higher risk of mental health issues, especially women after COVID-19.
7 citations
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April 2015 in “JAMA Dermatology” Finasteride's potential harms are hard to accurately measure.
10 citations
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May 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.
November 2014 in “Hair transplant forum international” Hair restoration surgery in patients with prior neurosurgery or radiation treatment can have risks like infection and poor wound healing, so it's important to discuss these with the patient.
31 citations
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February 2016 in “American Journal of Men's Health” Finasteride can cause serious emotional side effects; doctors should check patients' mental health history before prescribing.
12 citations
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August 2017 in “Pharmaceutical medicine” Most doctors know the thrombosis risk with Cyproterone/Ethinylestradiol, but some lack details on less common risks and patient instructions; educational materials are underused but useful.
January 2024 in “Authorea (Authorea)” Antiepileptic drugs cause cosmetic side effects like hair loss and weight gain, but patients still take their medication without it affecting their quality of life.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.
July 2023 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” Antiandrogens help improve developmental delays caused by valproic acid in rats.
24 citations
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December 2012 in “Behavioural Brain Research” Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.
Retinoids can cause skin issues and hair loss due to their effects on cell membranes.
March 2024 in “Journal of Neuroscience Research” Finasteride may reduce depression and anxiety in female rats and improve brain connectivity.
28 citations
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October 2011 in “British Journal of Pharmacology” Midazolam's seizure prevention is partly due to increased neurosteroid production.
9 citations
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January 2022 in “Biology” Male mice are more susceptible to autism-like changes from valproic acid than female mice.
March 2026 in “Frontiers in Bioscience-Elite” Duloxetine, escitalopram, and finasteride may be effective against bacteria and fungi.