March 2025 in “Journal of Endocrinology and Metabolism” Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.
November 2023 in “Scientific reports” The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
22 citations
,
January 2008 in “Physiological Research” Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
658 citations
,
June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
403 citations
,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
13 citations
,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
9 citations
,
January 2019 in “Postepy Dermatologii I Alergologii” The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.
Dutasteride is more effective and better tolerated than finasteride for hair loss treatment.
35 citations
,
May 2008 in “Drug and Alcohol Dependence” Female mice are less affected by certain substances that alter alcohol consumption compared to male mice.
2 citations
,
December 2022 in “Metabolites” Hair analysis shows low progesterone in anorexia patients, unchanged by short-term weight gain.
1 citations
,
November 2022 in “INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)” Vitamin D helps reduce depression in people with autoimmune thyroiditis and hypothyroidism.
49 citations
,
September 2015 in “Psychoneuroendocrinology” 5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.
5 citations
,
May 2018 in “Therapeutic advances in drug safety” Androgen use may increase the risk of stroke, but more research is needed.
Finasteride may cause depression and affect brain and gut health in male rats.
5 citations
,
June 2010 in “Universitas Psychologica” Progesterone helps protect against stress-related memory and behavior issues in rats.
16 citations
,
November 2018 in “Medicinal Chemistry” The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.
January 2026 in “Addiction Biology” Finasteride may help reduce alcohol cravings and related brain activity.
21 citations
,
March 2021 in “Frontiers in Neurology” The posterior cerebellum helps maintain balance by adapting to sensory inputs and self-motion.
April 2021 in “IntechOpen eBooks” Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
1 citations
,
June 2014 in “L Endocrinologo” Finasteride can cause lasting sexual and mood issues even after stopping the drug.
5 citations
,
April 2024 in “ACS Chemical Neuroscience” A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.
151 citations
,
December 2004 in “Neuropharmacology” Progesterone reduces anxiety without needing progesterone receptors.
49 citations
,
July 2008 in “Alcoholism Clinical and Experimental Research” Finasteride reduces alcohol consumption in mice by affecting brain chemicals.
25 citations
,
June 2017 in “Neuropharmacology” Increasing TSPO in the brain reduces anxiety and depression.
18 citations
,
June 2016 in “Brain Research” Increasing TSPO in the brain may help improve memory problems.
2 citations
,
June 2022 in “INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine)” Vitamin D can help reduce depression in people with hypothyroidism.
1 citations
,
June 2022 in “Frontiers in Neuroanatomy” Early hormones shape sex-specific differences in rat glands.
April 2026 in “Journal of Clinical Medicine” Stopping finasteride can lead to lasting sexual and psychological issues.
March 2024 in “Journal of Neuroscience Research” Finasteride may reduce depression and anxiety in female rats and improve brain connectivity.
11 citations
,
January 2020 in “World Journal of Traditional Chinese Medicine” Kidney-yang deficiency syndrome causes hormonal imbalances and various physical symptoms.