97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
122 citations
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July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
66 citations
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March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
109 citations
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June 2000 in “Development” Notch pathway activation causes abnormal hair layer development.
46 citations
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September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
June 2018 in “British Journal of Dermatology” Hair cells lose their nucleus and mitochondria in a specific order as they fill with keratin, which could help develop treatments for hair issues.
25 citations
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September 2015 in “Clinical Endocrinology” Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.
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August 1998 in “Journal of Investigative Dermatology”
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August 2014 in “Cellular reprogramming” Hair follicle stem cells need all reprogramming factors to become pluripotent.
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May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
January 2014 in “Institutional Repositories DataBase (IRDB)” Fibroblast spheres can form stem cells, but marker distribution needs more study.
88 citations
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April 1981 in “Molecular and cellular biochemistry” July 2025 in “Journal of Investigative Dermatology” Wnt and SHH pathways help form hair follicles by coordinating cell processes.
20 citations
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March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
23 citations
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January 2001 in “Chemical & Pharmaceutical Bulletin” New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
3 citations
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July 2018 in “Biomedicine & pharmacotherapy” Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.
71 citations
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May 1996 in “Journal of Investigative Dermatology” Ornithine decarboxylase is crucial for hair growth regulation in mice.
34 citations
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December 1991 in “Annals of the New York Academy of Sciences” Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
January 2021 in “Deep Blue (University of Michigan)” Androgen receptors in the brain affect metabolism and reproduction differently in males and females, and may help manage PCOS symptoms in females.
193 citations
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June 2007 in “The Plant Journal” GhDET2 is crucial for cotton fiber growth.
Nipple area expansion in mice needs both pregnancy hormones and mechanical strain.
62 citations
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August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
110 citations
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August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
Estrogen and its receptors play a key role in hair growth, with differences between males and females.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
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March 2025 in “Cytotechnology”
1 citations
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January 2017 in “Tohoku journal of experimental medicine” A woman's mature cystic teratoma caused her virilization by producing testosterone.