research Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-derived Peptides in Murine Skin
POMC-derived peptides are important for skin functions like immune response and stress management.
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570-600 / 1000+ resultsresearch Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation
Two peptides, RMYYY and VMYMI, may be effective anti-inflammatory drugs.
research Synthesis and biological screening of small molecule peptides based on the amino acid sequence of thymosin β4
Some synthesized peptides improved cell growth better than thymosin β4, VEGF, and minoxidil.
research The Relationship Between Glycine and Gephyrin in Synapses of the Rat Spinal Cord
Glycine is a key transmitter in rat spinal cord synapses, often alongside GABA.
research Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits
A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.
research Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
Increasing neuropeptide Y in the brain can slow aging signs in mice.
research Stimuli-Sensitive Nanocarriers for Diagnostic and Therapy
New nanocarriers were developed for safer, targeted drug delivery and diagnostics, showing promise for future medical use.
research Melatonin-Loaded Nanoparticles for Enhanced Antidepressant Effects and HPA Hormone Modulation
Melatonin-loaded nanoparticles improve antidepressant effects and HPA hormone balance better than regular melatonin.
research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research Dermatologia e Procedimentos Estéticos Ed. XVIII
Peptides improve skin health and treatments for hair loss and pregnancy-related skin issues are evolving.
research Phase-specific differential regulation of mechanical allodynia in a murine model of neuropathic pain by progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Effects of Collagen Peptides on Gene Expression Related to Hair Cycle Activation in the Skin
Collagen peptides may promote hair growth by activating certain genes in the skin.
research New steps forward in the neuroactive steroid field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Structural optimization of pep7, a small peptide extracted from epimorphin, for effective induction of hair follicle anagen
Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
research Histone deacetylase inhibitors promote neurosteroid‐mediated cell differentiation and enhance serotonin‐stimulated brain‐derived neurotrophic factor gene expression in rat C6 glioma cells
HDAC inhibitors help brain cells grow and improve brain function.
research Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR.
Neurotrophins regulate nerve growth by balancing promotion and suppression.
research Overview of Short Peptides for Hair Loss
Short peptides show promise as a new treatment for hair regrowth.
research Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin
Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
research LB1059 Neuromediators associated with neurogenic skin inflammation promote M2 differentiation of macrophages in human skin ex vivo
Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
research Role of Human Skin Antimicrobial Peptides in Psoriasis
Inflammation in psoriasis may trigger antimicrobial peptides and cell death.
research Evaluating purified exosome product and its role in neurologic and functional recovery following spinal cord injury in female rats
IT PEP may help recovery after spinal cord injury, but more research is needed.
research Changing the shape of hair with keratin peptides
Keratin peptides can change hair shape gently without harsh chemicals.
research Food-derived Crassostrea gigas peptides self-assembled supramolecules for scarless healing
Pacific oyster peptides may help wounds heal without scars.
research Palmitoylethanolamide-Incorporated Elastic Nano-Liposomes for Enhanced Transdermal Delivery and Anti-Inflammation
PEA-ENL improves skin delivery and reduces inflammation without side effects.
research Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals
Gut microbes significantly affect brain steroid levels.
research Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.