research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
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research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Defining the identity of mouse embryonic dermal fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.
research Chemotherapy-induced iatrogenic injury of skin: New drugs and new concepts
New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.
research Study on the mechanism of cadmium chloride pollution accelerating skin tissue metabolism disorder, aging and inhibiting hair regeneration
Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
research The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
research Dermatologic Implications of Glycemic Control Medications for Patients with Type 2 Diabetes Mellitus
Glycemic control medications for Type 2 diabetes can affect skin conditions like psoriasis.
research Phytochemical and Therapeutic Evaluation of Curcumin and Piperine in Alopecia
Curcumin and piperine may effectively and safely promote hair regrowth in alopecia.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Targeting specific cell interactions may help treat skin fibrosis.
research Genosomes: An introspection into transfection, future perspectives and applications
Genosomes are promising for safe and effective gene delivery in therapy.
research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
research Guidelines for the Use of Acitretin in Psoriasis
Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research Androgenetic alopecia and microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Pharmacological Activity and Clinical Use of PDRN
PDRN helps repair tissue and improve wound healing with a high safety profile.
research Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease‐associated psychological morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research Nitric Oxide Signal Transduction and Its Role in Skin Sensitization
Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.
research Compendium of polycystic ovarian syndrome and its relevance in glycation and diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells (SH-MSCs) on IL-10 and TNF- α Gene Expression (In Vivo Experimental Study in Male Rats of Wistar Strains Model of Fluconazole-Induced Alopecia)
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research The Rho GTPase exchange factor Vav2 promotes extensive age-dependent rewiring of the hair follicle stem cell transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research The Hair Follicle as a Dynamic Miniorgan
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Calreticulin: non‐endoplasmic reticulum functions in physiology and disease
Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
research Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome
Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
research Wound Healing and the Use of Medicinal Plants
Some medicinal plants can help heal wounds and may lead to new treatments.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances
Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
research Olfactory receptor OR2AT4 regulates human hair growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.