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The combination of TACE and Donafenib is effective and tolerable for treating unresectable liver cancer.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Tofacitinib, an arthritis drug, helped hair growth in alopecia universalis but long-term safety needs more research.

A mutation in the MAP2 gene causes reduced hair follicle density, leading to hairlessness.

Tofacitinib is safe and effective for treating moderate-to-severe alopecia areata.

Nicastrin deficiency may cause skin cell damage and pigmentation disorders in humans, similar to effects seen in fish.

Tofacitinib can cause skin eruptions similar to palmoplantar pustulosis.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

Nanofat with stem cells is promising for treating hair loss, scars, and skin rejuvenation.

TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.

Deleting Crif1 in mouse skin disrupts skin balance and hair growth.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

Loss of Pten in certain hair follicle stem cells increases skin cancer risk.

Topical tacalcitol ointment can help improve symptoms of EFFC.

TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.

Alternative treatments are needed when Tofacitinib alone fails for alopecia areata.

Mice with the naked gene have missing or abnormal hair cells.

The folate-cyclodextrin conjugate targets cancer cells more precisely, potentially reducing chemotherapy side effects.

Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.

The LEF-1 gene in cashmere goats was successfully cloned and analyzed, showing potential for improving cashmere production.

Oral tofacitinib is a promising treatment for beard hair loss in alopecia areata.

TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.

Familial frontal fibrosing alopecia affects premenopausal women too, and early diagnosis is important, but no proven medication exists yet.

Mitf plays a key role in melanoma progression and is linked to disease stage.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

The report expanded knowledge of MBTPS1-related disorders by identifying new symptoms.

Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.