4 citations
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September 2024 in “Cell Reports” Granulocyte colony stimulating factor helps heal wounds without scars.
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May 2001 in “Endocrinology” Mrp3 may aid in wound healing and hair growth.
4 citations
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June 2024 in “British Journal of Dermatology” EGFRi/MEKi treatments cause hair follicles to lose some immune protection, leading to inflammation.
Lack of Fgf21 slows hair growth by affecting gene interactions.
5 citations
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November 2013 in “Journal of Investigative Dermatology” The glucocorticoid receptor helps protect skin from tumors and other issues.
38 citations
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January 2011 in “PubMed” EGFR inhibitors often cause skin issues like acne and dryness, which can be managed with specific treatments.
November 2025 in “Biomolecules” FGF22 helps hair follicle stem cells grow and develop.
January 2025 in “SSRN Electronic Journal” 32 citations
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January 2010 in “Journal of Dermatological Science” Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.
55 citations
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April 2010 in “Cancer and Metastasis Reviews” TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
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July 2025 in “Frontiers in Genetics” FilaggrinHigh melanomas have active FGFR signaling and weak GNA14 and Th1 signatures.
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April 2016 in “International Journal of Oncology” GnRH treatment can reduce breast cancer cell invasion.
March 2026 in “Journal of Investigative Dermatology” 226 citations
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August 2006 in “Molecular and Cellular Biology” EGF signaling affects gene expression in skin cells, influencing hair growth and potentially cancer.
October 2024 in “Stem Cell Research & Therapy” CGF therapy may effectively treat psoriasis by reducing inflammation.
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July 2004 in “Molecular Medicine” Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
September 2023 in “World Rabbit Science” The FRZB gene slows hair growth in rabbits.
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May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
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November 1984 in “Journal of Investigative Dermatology”
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October 2025 γδ T cells help control tissue scarring and blood vessel growth in response to foreign objects.
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December 2015 in “PLoS ONE” Fibroblasts can be mistaken for neural cells, so functional validation is needed.
January 2026 in “Biochemical Pharmacology”
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February 2012 in “Supportive Care in Cancer” Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
60 citations
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March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
Keratinocytes can reverse the effects of the GNAQ oncogene, inhibiting melanoma cell growth.
March 2026 in “Stem Cell Reviews and Reports”
August 2013 in “Nature Reviews Drug Discovery” New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.
23 citations
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September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” NF-κB is crucial for different stages and types of hair growth in mice.
September 2004 in “Experimental Dermatology” Stress increases nerve growth factor, causing hair loss in mice.
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September 2020 in “Inflammation and Regeneration” WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.