61 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Beta-catenin is crucial for skin cell growth, development, and cancer formation.
61 citations
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November 2004 in “Annals of the Academy of Medicine Singapore” Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.
55 citations
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May 2017 in “Current stem cell research & therapy” Using fat-derived stem cells for hair loss treatment is safe and effective, improving hair growth and patient satisfaction.
55 citations
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March 2015 in “Carcinogenesis” WNT10A helps esophageal cancer cells spread and keep renewing themselves.
49 citations
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October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
47 citations
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October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
47 citations
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September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
46 citations
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June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
43 citations
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April 2021 in “Angiogenesis” Lymphatic vessels develop from various cell types and mechanisms, not just veins.
43 citations
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September 2017 in “Lasers in Surgery and Medicine” LED light therapy may help hair growth by activating certain cell pathways.
37 citations
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April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
37 citations
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March 2012 in “International Journal of Radiation Biology” Mobile phone radiation can cause DNA damage in human hair root cells.
32 citations
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August 2019 in “Nature Communications” Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.
31 citations
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April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
30 citations
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April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
29 citations
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July 2014 in “PloS one” Meis1 is crucial for skin health and tumor development.
28 citations
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August 2015 in “Journal of functional biomaterials” Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
28 citations
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February 2014 in “PLoS ONE” Epidermal stem cells on a special membrane helped mice regrow full skin with hair and functions.
25 citations
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July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
23 citations
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February 2015 in “International Journal of Molecular Sciences” Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
21 citations
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February 2017 in “PLoS ONE” RhoA helps skin stem cells grow, aiding wound healing.
20 citations
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September 2020 in “Journal of Translational Medicine” Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
19 citations
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September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
19 citations
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January 2018 in “BioMed Research International” miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
18 citations
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December 2020 in “Frontiers in cell and developmental biology” miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.
18 citations
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April 2019 in “Archives of Dermatological Research” Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.
17 citations
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June 2019 in “BMC genomics” Non-coding RNAs help control hair growth in cashmere goats.
17 citations
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April 2017 in “PLoS ONE” Hair follicle cells can become bone-like cells, useful for bone repair.
15 citations
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July 2017 in “PubMed” Injecting a mix of human skin and hair cells into mice can grow new hair.
14 citations
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March 2019 in “Journal of Cosmetic Dermatology” Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.