31 citations
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November 2022 in “Cold Spring Harbor Perspectives in Biology” Epithelial cells adapt and work together to heal skin wounds effectively.
417 citations
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September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
25 citations
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April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
118 citations
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January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
2 citations
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May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Rare Gli1+ fibroblasts are crucial for skin wound healing.
1 citations
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December 2023 Hair grows in cycles and changes with age, starting from fetal development.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
August 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF18 controls hair cycle rest and growth phases.
November 2025 in “Journal of Investigative Dermatology” Mesenchymal stiffness affects sweat gland cell development.
November 2014 in “Journal of Cell Biology” Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.
22 citations
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June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research provided new insights into the genetic factors contributing to hair loss and skin conditions by analyzing individual cells from the human scalp.
April 2023 in “Journal of Investigative Dermatology” Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
1 citations
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July 2025 in “Barrier Immunity” A holistic approach is crucial for treating skin disorders and restoring barrier function.
384 citations
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June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
11 citations
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December 2009 in “Cell stem cell” Sox2-expressing cells can help grow hair and heal skin.
March 2026 in “Mendeley Data” Basement membrane-like ECM supports fibroblast aggregation and cohesion.
23 citations
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May 2015 in “Science China Life Sciences” The microenvironment controls adult stem cells' behavior and fate.
January 2013 in “edoc (University of Basel)” TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
January 2022 in “Stem cell biology and regenerative medicine” New biofabrication technologies could lead to treatments for hair loss.
46 citations
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May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.
23 citations
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November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
14 citations
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June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
13 citations
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May 2017 in “Current Protocols in Stem Cell Biology” A method was developed to isolate and study hair follicle stem cells from mouse skin.
9 citations
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February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
9 citations
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September 2013 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
1 citations
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October 2016 in “Molecular biology of the cell” The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.
September 2022 in “Research Square (Research Square)” Macrophages help maintain mammary stem cells and balance through specific signaling.
82 citations
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March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.