research The Synthesis of 2,2-BIS(1-INDOL-3-YL)Acenaphthylene-1(2)-Ones Using Nanocatalysis: Fluorescent Sensing for Cu2+ Ions
A new compound was made to detect copper ions effectively.
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research Minoxidil
Minoxidil effectively treats severe hypertension but has notable side effects.
research Correction to “Multistage Transdermal Nitric Oxide Delivery System for the Efficient Treatment of Androgenic Alopecia”
research NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium
NFAT5 triggers atherosclerosis under stress by activating inflammation in blood vessels.
research Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin
Light-activated hyaluronic acid derivatives can enhance skin healing and regeneration.
research A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia
Niacin derivatives may increase hair fullness in women with hair loss.
research Synthesis and structure–activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands
The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
research Inorganic Nanozymes: Prospects for Disease Treatments and Detection Applications
Nanozymes could improve disease treatment and detection.
research Effects of carpronium chloride on the microvascular blood flow in rat mesentery using intravital videomicroscopy.
Carpronium chloride increases blood flow by widening small blood vessels.
research Synthesis of avicequinone c and analogs toward the study of 5α-reductase inhibitory activity
2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.
![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/research/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
research Boosting Skin Microcirculation for Androgenetic Alopecia: Does It Work?
DMG-Na may help reduce hair loss and improve hair growth, but more research is needed.
research PNU 157706, a novel dual type I and II5α-reductase inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Chromolaena odorata layered-nitrile rubber polymer transdermal patch enhanced wound healing in vivo
The Chromolaena odorata patch significantly speeds up wound healing.
research Anti‐Fertility Effects of Amlodipine in Adult Male Wistar Rats
Amlodipine impairs fertility in male rats by affecting sperm and testicular structure.
research Sulphate conjugation of minoxidil in rat skin
Rat skin can convert minoxidil into its active form, aiding hair growth.
research Non-rhizobial nodule endophytes improve nodulation, change root exudation pattern and promote the growth of lentil, for prospective application in fallow soil
Certain bacteria can boost lentil growth and improve soil used for farming.
research Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study
Nitrogen mustard was not very effective for hair regrowth in alopecia areata and has potential skin cancer risk.
research Prolonged hypotension induced by ingesting a topical minoxidil solution: analysis of minoxidil and its metabolites
Swallowing a lot of minoxidil, a hair growth liquid, can cause severe and long-lasting low blood pressure.
research GIDA KATKI MADDESİ SODYUM BENZOATIN OKSİDATİF STRES VE GENOTOKSİSİTE ÜZERİNE ETKİLERİNİN ARAŞTIRILMASI
Sodium benzoate at higher doses can harm kidney and liver functions and cause oxidative stress and DNA damage.
research 1317 Nicotinic acid suppresses sebaceous lipid synthesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2)
Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
research Effect of minoxidil on blood pressure and hemodynamics in severe hypertension
research The Enzymic Derivation of Citrulline Residues from Arginine Residues In Situ during the Biosynthesis of Hair Proteins that are Cross-Linked by Isopeptide Bonds
Hair follicles have an enzyme that converts arginine to citrulline in proteins.
research Profound bradycardia after addition of diltiazem to a beta blocker.
Adding diltiazem to a beta blocker can cause dangerously slow heart rates.
research iNOS inhibits hair regeneration in obese diabetic (ob/ob) mice
iNOS contributes to hair loss in obese diabetic mice and blocking it may encourage hair growth.
research Topical niacinamide does not stimulate hair growth based on the existing body of evidence
Niacinamide does not promote hair growth.
research Refractory shock following ingestion of topical minoxidil solution
A man experienced life-threatening shock after swallowing hair growth solution.
research Vitamin C Deficiency-Induced Pulmonary Arterial Hypertension
Vitamin C supplementation can resolve pulmonary arterial hypertension caused by vitamin C deficiency.
research Determination of Minoxidil by Bleaching the Permanganate Carrier Solution in a Flow-Based Spectrophotometric System
The method quickly and accurately measures minoxidil in drugs, comparable to standard techniques.
research Testosterone 5.ALPHA.-Reductase Inhibitory Active Constituents of Piper nigrum Leaf
Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.