13 citations
,
May 2011 in “Bioorganic & Medicinal Chemistry” Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
January 2022 in “Springer eBooks” August 2022 in “Journal of The American Academy of Dermatology” A 5-mg dose of oral minoxidil slightly lowers blood pressure temporarily, especially in those with higher initial blood pressure.
1 citations
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November 2015 in “Cochrane library” 5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
December 2015 in “Vascular Pharmacology” Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.
61 citations
,
April 2021 in “Regenerative Biomaterials” 3D bioprinted hydrogel scaffolds with stem cells and nitric oxide help heal severe burns faster.
4 citations
,
September 2006 in “European Urology Supplements” Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.
1 citations
,
August 2017 Minoxidil helps stimulate hair growth and enlarge small follicles in common hair loss, but doesn't stop it, and its effects can be boosted when combined with finasteride.
11 citations
,
December 2018 in “Assay and Drug Development Technologies” Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
February 2026 in “The Journal of Sexual Medicine” GnRH agonists can help manage recurrent priapism in sickle cell patients, but long-term safety is unclear.
195 citations
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February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
August 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Dutasteride effectively treats hair loss and prostate issues.
5 citations
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January 2001 in “Advances in protein chemistry” 5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
7 citations
,
January 2021 in “The Journal of Sexual Medicine” Testosterone with dutasteride improves muscle strength and body composition in trans men.
6 citations
,
January 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil can be effective for hair loss but should be avoided in people with certain heart conditions and severe liver problems.
2 citations
,
April 2021 in “Canadian Journal of Urology” Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
40 citations
,
April 1999 in “Drugs” Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
7 citations
,
October 2009 in “Journal of the American Geriatrics Society” Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.
5 citations
,
September 2015 in “Medical hypotheses” Topical sulfonylurea may reduce excessive hair growth caused by certain medications.
4 citations
,
February 2024 in “Frontiers in Cardiovascular Medicine” Tai Chi and Wuqinxi, combined with medication, effectively lower blood pressure.
43 citations
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January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
January 2022 in “Asian journal of Current Research in Clinical Cancer” Some dibenzo compounds might help treat cancer with fewer side effects.
November 2023 in “European heart journal” Finasteride improves heart function and balance in aging and obese male rats by reducing oxidative stress.
Finasteride and dutasteride are not recommended for feminizing therapy due to limited effectiveness and potential risks.
Dexmedetomidine-loaded microneedles effectively reduce pain without sedation.
January 2018 in “journal of applied pharmaceutical science” Nettle juice gel may help treat hair loss by improving blood flow and promoting new hair growth.
29 citations
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April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
December 2025 in “Journal of Drug Discovery and Therapeutics” Spanlastics improve drug delivery by enhancing bioavailability and targeting, reducing side effects.
August 2021 in “Josai University Repository of Academia (Josai University)” The nanoparticles improved minoxidil's skin absorption, making them promising for skin treatments.
January 2020 in “Figshare” Finasteride worsens heart damage but reduces cell toxicity caused by nandrolone decanoate.