research The Role of Other Peripheral Nerve Blocks
Peripheral nerve blocks are a safe and effective way to treat various headaches and provide lasting pain relief.
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research 1430 Modeling the onset of senescence associated secretory phenotype predicts therapeutic targets
The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
research Author response: Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis
Neutrophils are important for causing chronic itch in atopic dermatitis, and blocking the CXCR3 receptor may reduce this itch.
research The sensory innervation of primate facial skin. II. Vermilion border and mucosa of lip
Monkey lips have dense sensory nerves similar to those in other skin areas, explaining their sensitivity.
research Pain management in photoepilation
Effective pain relief methods for photoepilation include topical anesthetics, cooling devices, and skin stimulation.
research Hyperinnervation inhibits organ-level regeneration in mammalian skin
Reducing nerve growth can help skin regenerate after birth.
research Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways
Noggin promotes skin tumors by activating certain cell signaling pathways.
research Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3
TRPV3 is important for skin health and could be a target for treating skin diseases.
research Role of Transient Receptor Potential Vanilloid 4 Channel in Skin Physiology and Pathology
TRPV4 channel affects skin health and could be a target for treating skin disorders.
research TRPV3 as a Therapeutic Target for Itch
Blocking TRPV3 may help treat itch in dry skin conditions.
research The existence of a linear system consisting of sympathetic endings in rat skin
Rat skin has a linear system of nerve fibers linked to hair follicles and muscles.
research NIEFARMAKOLOGICZNA METODA REDUKCJI BÓLU FIZYCZNEGO POPRZEZ ZMIANĘ RODZAJU UWAGI. OPIS PRZYPADKÓW I METODY
Shifting attention can reduce physical pain.
research The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway
Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.
research Multipotent nestin‐expressing hair follicle stem cells
Hair follicle stem cells can turn into various cell types and help repair nerves.
research Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice
Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.
research Before & beyond the pain – Allostatic load, central sensitivity and their role in health and function
Recognizing and managing central sensitization and stress is crucial for treating chronic pain.
research Upregulation of genes orchestrating keratinocyte differentiation, including the novel marker gene ID2, by contact sensitizers in human bulge‐derived keratinocytes
The ID2 gene can help distinguish between sensitizers and irritants in skin cells.
research Synaptic relationships between hair follicle afferents and neurones expressing GABA and glycine‐like immunoreactivity in the spinal cord of the rat
Glycine likely affects dendrites connected to hair follicle terminals in rats.
research 301 The Spectrum of PLEC Sequence Variants and Related Plectinopathies Including Novel Association with Epidermolysis Bullosa Pruriginosa
Neutrophils quickly respond to skin injury.
research Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis
Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
research Ectopic olfactory receptors in human: New therapeutic possibilities
Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.
research The development of cutaneous afferent pathways in fetal sheep: a structural and functional study
Fetal sheep develop skin nerve pathways and responses to touch and heat between 75 and 134 days of gestation.
research 0960 Evidence for resident memory T cells and necroptosis as drivers of fibrosis in eosinophilic fasciitis and morphea
Resident memory T cells and necroptosis may drive fibrosis in eosinophilic fasciitis and morphea.
research Melanocortin receptors in fibroblastic cell types of the skin –in vitro and in vivo expression and functional relevance
MC-1R is present in skin cells and may help reduce inflammation.
research GPCRs as key regulators in wound healing
GPCRs are vital for wound healing by affecting cell growth and immune response.
research Occipital Neuralgia after Hair Transplantation and Its Treatment
A man's severe head pain after hair transplant was greatly relieved by pulsed radiofrequency treatment.
research PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect
A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research [Transplanted epidermal neural crest stem cell in a peripheral nerve gap].
Epidermal neural crest stem cells from hair follicles can help repair nerve injuries.
research Complex Regional Pain Syndrome I (Reflex Sympathetic Dystrophy)
CRPS type I is a complex pain condition with no proven cure, requiring personalized treatment.