research Impact of Reporter Type on Signal Detection of Cancer Therapy–Induced Alopecia: A Hypothesis-Generating Study Using the FDA Adverse Event Reporting System
Reporter characteristics affect detection of hair loss from cancer therapy.
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research Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics
Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
research Succinic Acid in Cosmetics and Aesthetic Dermatology: Biological Roles and Applications
Succinic acid helps improve skin conditions like acne and rosacea.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research ENZYMES
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Iron Deficiency in Immune-Mediated Inflammatory Skin Diseases: A Missing Link Between Systemic Inflammation, Immunometabolism, and Disease Burden
Iron deficiency worsens inflammatory skin diseases by disrupting iron balance and increasing inflammation.
research A State-of-the-Art Overview on (Epi)Genomics and Personalized Skin Rejuvenating Strategies
Personalized skin rejuvenation using genomics shows promise but needs more research.
research Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats
Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
research Immunopathology and Immunotherapy of Inflammatory Skin Diseases
New targeted immunotherapies are improving treatment for inflammatory skin diseases.
research Significance of stress keratin expression in normal and diseased epithelia
Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
research Growth Hormone and the Human Hair Follicle
Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.
research Inflammatory bowel disease: pathogenesis, diagnosis and current therapeutic approach
IBD treatment is complex and requires personalized approaches due to varying patient responses.
research 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism
24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.
research The ATP sensitive potassium channel (KATP) is a novel target for migraine drug development
Blocking the KATP channel may help treat migraines.
research Hair Histology and Glycosaminoglycans Distribution Probed by Infrared Spectral Imaging: Focus on Heparan Sulfate Proteoglycan and Glypican-1 during Hair Growth Cycle
Infrared spectral imaging can map hair growth proteins and sugars without staining.
research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
research Ancient botanicals and the skin: Defining dermatologic ethnophytoconvergence as a translational framework for pharmacognosy
Cross-cultural plant knowledge can improve skin treatments.
research Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231
Glibenclamide slows breast cancer cell growth by stopping cell division.
research Aging in the sebaceous gland
Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
research II Consensus of the Brazilian Society of Dermatology for the treatment of alopecia areata
Treat alopecia areata with personalized plans, using corticosteroids for mild cases and Janus Kinase inhibitors for severe cases, while also offering psychological support.
research Exploring extracellular vesicles as novel therapeutic agents for intervertebral disc degeneration: delivery, applications, and mechanisms
Extracellular vesicles may help prevent and repair spine disc degeneration.
research Osteogenic Potential of Mesenchymal Stem Cells from Adipose Tissue, Bone Marrow and Hair Follicle Outer Root Sheath in a 3D Crosslinked Gelatin-Based Hydrogel
Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
research A Systematic Review of the Effects of Exercise on Hormones in Women with Polycystic Ovary Syndrome
Exercise, especially vigorous aerobic and resistance training, can improve hormone levels in women with PCOS.
research Food Bioactive Compounds and Emerging Techniques for Their Extraction: Polyphenols as a Case Study
Polyphenols in plant foods help prevent diseases and have potential uses in food, cosmetics, and more.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research The therapeutic efficacy of mesenchymal stem cells and their extracellular vesicles in the treatment of diverse skin diseases
Mesenchymal stem cells and their vesicles may effectively treat skin diseases, but more research is needed.
research Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders
Exosomes could be a promising way to help repair skin and treat skin disorders.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.