36 citations
,
May 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
October 2025 in “Journal of the Endocrine Society” Goserelin injections can effectively manage hyperandrogenism symptoms in postmenopausal women who can't have surgery.
October 2019 in “Bioscientifica Proceedings” Androgens may improve pig reproduction by enhancing ovulation and litter size.
83 citations
,
December 2004 in “American Journal of Obstetrics and Gynecology”
4 citations
,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
2 citations
,
March 1977 in “British Journal of Dermatology” Nandrolone phenylpropionate injections thickened the skin and enlarged oil glands in female hairless hamsters.
92 citations
,
February 2005 in “Endocrinology” Estrogen receptors affect hair growth, with ER beta slowing down the hair cycle changes caused by ER alpha.
139 citations
,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
3 citations
,
February 2013 in “PubMed” 5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.
1 citations
,
December 2022 in “Pharmaceuticals” Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
April 2024 in “Expert opinion on emerging drugs” New treatments for male hair loss are being explored to improve effectiveness and reduce side effects.
48 citations
,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” DHT increases scalp heat, causing hair loss.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” DHT increases scalp heat, causing hair loss.
May 2008 in “Trends in Urology Gynaecology & Sexual Health” Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
9 citations
,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
7 citations
,
March 2013 in “British Journal of Dermatology” No genetic link between prostaglandins and hair loss found.
October 2022 in “The Korean Journal of Physiology and Pharmacology” Targeting the PGD2-DP2 pathway may help treat hair loss.
November 2023 in “Bioorganic Chemistry” Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
January 2008 in “Acta Anatomica Sinica” Minoxidil promotes hair growth by delaying the hair's resting phase.
December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
44 citations
,
January 1999 in “Advances in pharmacology” The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.
Anti-androgens can help treat tough skin conditions like severe acne and excessive hair growth.
23 citations
,
October 2015 in “Andrology” New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
1 citations
,
April 2017 in “Drugs & Therapy Perspectives” Use antiandrogens and other treatments for hair loss.
October 2024 in “Journal of the Endocrine Society” Gender-affirming hormone therapy affects metabolism differently based on treatment type.
3 citations
,
December 2020 in “Problemy e̊ndokrinologii” Male hormones may make COVID-19 worse, while substances that block these hormones could lessen symptoms.
108 citations
,
January 2010 in “International Journal of Andrology” Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.
April 2021 in “IntechOpen eBooks” Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
160 citations
,
April 2008 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” DHT in the human prostate is produced through multiple pathways, not just from testosterone.