92 citations
,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
1 citations
,
May 2025 in “Current Issues in Molecular Biology” Centipeda minima and brevilin A protect skin cells from damage and aging.
44 citations
,
May 1997 in “Journal of Biological Chemistry” The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
67 citations
,
August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
7 citations
,
December 2004 in “Medicine” Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.
November 2023 in “Biomolecules” The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
3 citations
,
April 2012 in “Cancer research” Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.
49 citations
,
December 2009 in “Journal of Investigative Dermatology” Thyroid function affects skin health, with a complex interaction between the two.
5 citations
,
January 2009 in “Dermato-endocrinology” ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
22 citations
,
June 2012 in “Journal of Investigative Dermatology” Adiponectin may stimulate hair growth and could be a potential treatment for promoting hair growth.
28 citations
,
August 2003 in “Steroids” Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
27 citations
,
January 1993 in “Archives of Dermatological Research” Hair follicles can grow and increase DNA synthesis in a serum-free environment, and minoxidil sulphate boosts this process.
18 citations
,
April 1986 in “International Journal of Cosmetic Science” Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.
5 citations
,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
June 2023 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.
150 citations
,
August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
99 citations
,
January 2004 in “Journal of Biological Chemistry” Methylprednisolone helps skin cells stick together better in pemphigus vulgaris.
40 citations
,
June 2013 in “Biomaterials” Scientists created 3D hair-like structures that could help study hair growth and test treatments.
16 citations
,
June 2019 in “Journal of Investigative Dermatology” miR-21 increases skin aging by reducing SATB1, affecting skin cell function.
3 citations
,
October 2024 in “International Journal of Molecular Sciences” CRET therapy affects inflammation in skin cells by changing cytokine levels and activating certain proteins.
18 citations
,
May 2022 in “Stem Cell Research & Therapy” Green OLED light improves stem cell effectiveness for better wound healing.
1 citations
,
July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
215 citations
,
March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
78 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.
43 citations
,
October 2013 in “Journal of Investigative Dermatology” Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.
January 2025 in “International Journal of Molecular Sciences” Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.
June 2020 in “Journal of Investigative Dermatology” Tiny particles from skin cells can help activate hair growth.
27 citations
,
December 2014 in “Current problems in dermatology” Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.
209 citations
,
September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
47 citations
,
April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.