Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
17 citations
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April 1972 in “PubMed” Minoxidil lowers blood pressure and spreads throughout the body in normal rats.
April 2017 in “The journal of sexual medicine” 5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.
April 2017 in “The Journal of urology/The journal of urology” SHH protein helps nerve regeneration in hypertensive rats.
April 2017 in “The Journal of urology/The journal of urology” Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.
23 citations
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December 2008 in “Current medicinal chemistry” Stimulating sensory neurons can increase IGF-I production, which may help treat various diseases and improve tissue health.
19 citations
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March 1990 in “Journal of Cardiovascular Pharmacology” Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.
13 citations
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December 2017 in “CNS Neuroscience & Therapeutics” Finasteride affects young male rats' brain function and behavior negatively.
May 2020 in “Fertility and Sterility” Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.
April 2011 in “The FASEB Journal” Amlodipine impairs fertility in male rats by affecting sperm and testicular structure.
6 citations
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November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
43 citations
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January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
58 citations
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January 2003 in “Biological & Pharmaceutical Bulletin” Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.
3 citations
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March 2017 in “Regulatory toxicology and pharmacology” Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
January 2015 in “Elsevier eBooks” Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.
28 citations
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August 2013 in “Hypertension” Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
December 2010 in “OhioLink ETD Center (Ohio Library and Information Network)” Sry may regulate fatty acid metabolism and shows different expression levels in rat tissues.
18 citations
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February 2024 in “Nutrients” A new pomegranate extract lowers blood pressure and has health benefits.
22 citations
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February 2018 in “International Journal of Pharmacy and Pharmaceutical Sciences” Peperomia pellucida shows promise for developing new therapeutic drugs.
45 citations
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October 1988 in “British Journal of Clinical Pharmacology” Using topical minoxidil for baldness can cause heart problems, especially in those with heart disease.
17 citations
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April 1975 in “The Journal of Pediatrics” Minoxidil effectively controls severe high blood pressure in children with few side effects.
53 citations
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January 1993 in “Biochemical Pharmacology” Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.
45 citations
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January 1981 in “Annals of Internal Medicine” Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
27 citations
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August 1984 in “Experimental and Molecular Pathology”
35 citations
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August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
180 citations
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July 1973 in “The New England Journal of Medicine” Minoxidil effectively lowers blood pressure with few side effects.
109 citations
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July 1984 in “Circulation” Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.
96 citations
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October 1981 in “Drugs” Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
57 citations
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January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
55 citations
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October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.