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Protac Degraders of Androgen Receptor-Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration

research PROTAC Degraders of Androgen Receptor‐Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration

December 2022 in “Small methods”

A new hair loss treatment using dissolving microneedles was found to speed up hair growth and was more effective than daily use of common hair growth drugs.

research Synthesis of N-Substituted 3-Oxo-17b- carboxamide-4-aza-5a-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes

4 citations , January 1998 in “Heterocycles”

Researchers made two new compounds that could be used for medicine.

research [Alopecia androgenetica and its local treatment with estrogen- and corticosteroid externa].

7 citations , October 1974 in “PubMed”

Topical estrogens improved hair growth in about half of the patients.

research Cationic Ionic Liquid-Liposome Nanoplatform for Transdermal asiRNA Delivery: A Unified Therapy for Androgen-Dependent Dermatoses

January 2025 in “SSRN Electronic Journal”

research Discovery of Nonsteroidal Androgens

209 citations , March 1998 in “Biochemical and biophysical research communications”

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

research Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone. Letter.

1 citations , February 2022 in “The Journal of Urology”

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

A Novel More Effective Topical Therapeutic Approach for Treatment of Androgenetic Alopecia: First in Human Trial Results for Topical ET-02

research LB1158 A novel more effective topical therapeutic approach for treatment of androgenetic alopecia: First in human trial results for topical ET-02

July 2025 in “Journal of Investigative Dermatology”

5% ET-02 is a more effective and safe treatment for hair loss than current options.

research NMR Study on Finasteride

January 2007 in “Chinese Journal of Pharmaceuticals”

The study successfully identified the structure of finasteride.

research Clinical study of combined prednisone with minoxidil in treatment of the androgenetic alopecia

January 2010 in “Chinese Journal of Postgraduates of Medicine”

Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3

research Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3

15 citations , April 2008 in “Steroids”

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

research Steroid inhibitors of androgen-potentiated actions on skin

4 citations , July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.

A Comparison of the Efficacy, Relapse Rate, and Side Effects Among Three Modalities of Systemic Corticosteroid Therapy for Alopecia Areata

research A Comparison of the Efficacy, Relapse Rate and Side Effects among Three Modalities of Systemic Corticosteroid Therapy for Alopecia Areata

January 2007 in “Yearbook of Dermatology and Dermatologic Surgery”

Intramuscular triamcinolone and pulse therapy with oral predonine are effective for alopecia areata with manageable side effects, but better relapse prevention is needed.

Optimization and Transfollicular Delivery of Finasteride Loaded PLGA Nanoparticles Laden Carbopol Gel for Hair Growth Stimulation

research Optimization and Transfollicular Delivery of Finasteride Loaded PLGA Nanoparticles Laden Carbopol Gel for Treatment of Hair Growth Stimulation

February 2024 in “Current Bioactive Compounds”

The new gel formulation effectively delivers Finasteride for hair growth treatment without skin irritation.

Androstenedione: Risks and Lack of Efficacy in Athletes

research Androstenedione

February 1999 in “Strength and Conditioning Journal”

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid, and Carnitine-Containing Compound in Prostate and Hair Follicle Cell-Based Assays

research Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays

3 citations , March 2016 in “Phytotherapy Research”

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

research Systemic Steroids for Treatment of Alopecia Areata

9 citations , December 1977 in “Archives of Dermatology”

Systemic steroids can effectively treat alopecia areata with manageable side effects.

Rare Steroid Cell Tumor Found in Northern Brazil: Case Report

research Rare steroid cell tumor found in region North Brazil: case report

January 2023 in “Seven Editora eBooks”

A rare ovarian tumor was diagnosed in a woman from North Brazil, and surgery is the preferred treatment.

In Vitro and In Vivo Effects of 17β-N-(4-Phenylcarbamoyl) Androst-4-en-3-one Derivatives as 5α-Reductase Inhibitors on Androgen-Dependent Glands

research In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands

September 2020 in “Current Enzyme Inhibition”

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.