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research Arabidopsis ADF8 and ADF11 contribute to root hair growth to respond to hormone and environmental signals

February 2026 in “The Plant Journal”

ADF8 and ADF11 help root hairs grow by responding to hormones and environmental signals.

research LEKTI: Netherton Syndrome and Atopic Dermatitis

1 citations , February 2013 in “InTech eBooks”

LEKTI is crucial for skin barrier and immune function, affecting conditions like Netherton syndrome and atopic dermatitis.

research The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis

19 citations , March 2022 in “Molecular therapy. Nucleic acids”

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

research Niacin deficiency increases the sensitivity of rats to the short and long term effects of ethylnitrosourea treatment.

21 citations , January 1999 in “Molecular and Cellular Biochemistry”

Niacin deficiency makes rats more sensitive to cancer-causing chemicals.

research Coregulation of Genetic Programs by the Transcription Factors NFIB and STAT5

20 citations , March 2014 in “Molecular Endocrinology”

NFIB and STAT5 work together to control specific genetic programs in cells.

Cell Wall-Associated Root Hair Specific 10, a Proline-Rich Receptor-Like Kinase, Is a Negative Modulator of Arabidopsis Root Hair Growth

research Cell wall-associated ROOT HAIR SPECIFIC 10, a proline-rich receptor-like kinase, is a negative modulator of Arabidopsis root hair growth

33 citations , February 2016 in “Journal of Experimental Botany”

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

research Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro

24 citations , February 2015 in “Experimental Cell Research”

NFIC helps human dental stem cells grow and become tooth-like cells.

research Characterization of the Human Hair Keratin–Associated Protein 2 (KRTAP2) Gene Family

52 citations , April 2012 in “Journal of Investigative Dermatology”

KRTAP2 genes are crucial for hair structure and may impact hair disorders and treatments.

A New Mutation Resulting in the Truncation of the TRAF6-Interacting Domain of XEDAR: A Possible Novel Cause of Hypohidrotic Ectodermal Dysplasia

research A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia: Figure 1

17 citations , August 2012 in “Journal of Medical Genetics”

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease

research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease

26 citations , June 2018 in “The journal of immunology/The Journal of immunology”

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

research The Arabidopsis Receptor-like Kinase CAP1 Promotes Shoot Growth under Ammonium Stress

5 citations , October 2022 in “Biology”

CAP1 helps Arabidopsis plants grow better under ammonium stress.

research Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71 rco12 and Krt71 rco13

51 citations , December 2006 in “Mammalian Genome”

research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models

5 citations , August 2019 in “iScience”

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

research RSL4 regulatory network acts as an early driver of root hair growth at low temperature in Arabidopsis thaliana

April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

A gene network led by RSL4 is crucial for early root hair growth in response to cold in Arabidopsis thaliana.

research Primary Involvement of NADPH Oxidase 4 in Hypoxia-Induced Generation of Reactive Oxygen Species in Adipose-Derived Stem Cells

67 citations , December 2011 in “Stem Cells and Development”

NADPH oxidase 4 is key for stem cell activity and growth under low oxygen.

research Modulating Aging and Aging-related Symptoms Using Endogenous Small Molecules

January 2019

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

research Fibrotic enzymes modulate wound‐induced skin tumorigenesis

15 citations , March 2021 in “EMBO Reports”

PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.

research Single nucleotide polymorphisms in the KRT82 promoter region modulate irregular thickening and patchiness in the dorsal skin of New Zealand rabbits

2 citations , May 2024 in “BMC Genomics”

Certain genetic changes in the KRT82 gene may cause patchy skin in New Zealand rabbits.

research Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs

32 citations , March 2018 in “Neoplasia”

Nephronectin is linked to worse breast cancer outcomes and helps cancer spread.

Metabolic and Transcriptomic Reprogramming During Contact Inhibition-Induced Quiescence Is Mediated by YAP-Dependent and YAP-Independent Mechanisms

research Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms

11 citations , August 2024 in “Nature Communications”

Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.

research LB1007 Systemic treatment with a KLK5 inhibitor shows efficacy in a murine model of Netherton syndrome

July 2024 in “Journal of Investigative Dermatology”

A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.

research Characterization of the Human Hair Shaft Cuticle–Specific Keratin-Associated Protein 10 Family

11 citations , May 2013 in “Journal of Investigative Dermatology”

KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.

research Runx1 transcription factor is involved in the regulation of KAP5 gene expression in human hair follicles

6 citations , January 2006 in “Journal of dermatological science”

Runx1 helps control the KAP5 gene in human hair follicles.

research Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis

303 citations , October 2000 in “Nature”

RXRα is crucial for hair growth and skin cell function.

research LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth

43 citations , January 2016 in “Development”

LHX2 is essential for hair follicle development, controlled by NF-κB and TGFβ2 signaling.

research Targeting noncanonical nuclear factor kappa B signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha

June 2026 in “Strathprints: The University of Strathclyde institutional repository (University of Strathclyde)”

Topical IKKα inhibitors may help prevent CCS tumours.

Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert

research Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 2111In fond memory of Dr Peter Steinert.

62 citations , January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

research Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

475 citations , October 2006 in “Proceedings of the National Academy of Sciences”

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

research A CLE14 Signalling Cascade Promotes Arabidopsis Root Hair Elongation

3 citations , May 2025 in “Plant Cell & Environment”

CLE14 peptide promotes root hair growth in Arabidopsis.

research Influence of Myosin Regulatory Light Chain and Myosin Light Chain Kinase on the Physiological Function of Inner Ear Hair Cells

April 2025 in “Journal of the Association for Research in Otolaryngology”

NM2 and RLC phosphorylation are essential for normal inner ear hair cell function.

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