97 citations
,
March 2006 in “Journal of Investigative Dermatology” Mutations in the DSG4 gene cause a severe form of brittle hair and skin issues.
49 citations
,
January 2006 in “Developmental Dynamics” Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.
38 citations
,
January 2012 in “Journal of Korean Medical Science” Early-onset alopecia, especially with a family history, leads to worse outcomes and more related health issues.
26 citations
,
January 2016 in “Journal of cutaneous and aesthetic surgery” Hair transplant combining scalp and beard hair with PRP was successful for scarring alopecia.
24 citations
,
January 2018 in “International Journal of Trichology” Tofacitinib helped regrow hair in patients with alopecia, with few side effects.
14 citations
,
March 2014 in “Acta anaesthesiologica Taiwanica” A man developed rare complications after nose surgery, stressing the need for better prevention.
13 citations
,
April 2022 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.
10 citations
,
January 2014 in “International Journal of Trichology” Sarcoidosis can cause scarring hair loss on the scalp, which is rare.
9 citations
,
August 2021 in “Journal of clinical medicine” Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
6 citations
,
September 2022 in “Vaccines” Some people developed alopecia areata after COVID-19 vaccination, but it's not caused by the vaccine and most improved with treatment.
5 citations
,
January 2024 in “JID Innovations” CCCA involves immune response and metabolism issues, suggesting new treatment options.
5 citations
,
October 2019 in “JAAD Case Reports” These hair loss conditions might be part of a spectrum, not separate issues.
4 citations
,
January 2020 in “Skin appendage disorders” A woman with an unusual pattern of hair loss was confirmed to have Frontal Fibrosing Alopecia and treated with specific medications.
4 citations
,
January 2015 in “Case Reports in Rheumatology” Early recognition and management of connective tissue diseases like lupus are crucial in young patients.
3 citations
,
December 2024 in “International Journal of Dermatology” Premature hair graying is caused by genetics, stress, and lifestyle, and affects mental health.
3 citations
,
September 2024 in “JAAD reviews.” Topical corticosteroids are recommended first for treating pediatric alopecia areata due to their safety and ease of use.
3 citations
,
September 2021 in “JAAD case reports” Denosumab, a bone loss treatment, may cause hair loss and skin reactions due to immune system effects.
3 citations
,
January 2019 in “Skin Appendage Disorders” People with alopecia areata may also have allergic rhinitis and should be checked for respiratory allergies.
2 citations
,
September 2022 in “Annals of Medicine and Surgery” A man with a rare scalp cancer was successfully treated, highlighting the need for early management to prevent spread and complications.
2 citations
,
August 2022 in “Frontiers in Immunology” Microneedling with betamethasone led to almost complete hair regrowth in severe alopecia areata.
2 citations
,
January 2019 in “Skin appendage disorders” Early diagnosis and quick treatment improve life quality for FFA patients.
1 citations
,
December 2024 in “ACS Biomaterials Science & Engineering” The patches could quickly deliver epilepsy treatment and reduce seizures.
1 citations
,
March 2023 in “Clinical, Cosmetic and Investigational Dermatology” Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.
1 citations
,
May 2017 in “InTech eBooks” The chapter explains common scalp conditions, including infections, infestations, and tumors.
1 citations
,
January 2016 in “Journal of Headache & Pain Management” Discontinuing topical minoxidil can resolve headaches and dizziness.
June 2026 in “Frontiers in Medicine” The serum improved hair growth and condition after hair transplant.
The serum improved hair growth and comfort after hair transplant.
May 2026 in “Journal of Neurosciences in Rural Practice” Tofacitinib may cause nerve damage in the brain, so monitor for neurological symptoms.
February 2026 in “International Journal of Molecular Sciences” Muscarinic acetylcholine receptors in skin cells help regulate and promote hair growth.
January 2026 in “Clinical Case Reports” A 6-year-old girl had both monilethrix and trichorrhexis nodosa, causing brittle hair, with minimal improvement from treatment.