12 citations
,
April 1987 in “PubMed” Low-dose spironolactone is safe and effective for treating hirsutism.
6 citations
,
January 1977 in “Archives of dermatological research”
11 citations
,
February 2016 in “Current Medicinal Chemistry” New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
1 citations
,
May 2019 in “The Journal of Sexual Medicine” Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.
January 2006 in “Zhongguo yaofang” The market for these drugs is expected to grow.
6 citations
,
January 2020 in “BMC Neuroscience” Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.
November 2025 in “Contraception” COC use doesn't increase hair stress hormone levels, but hair treatments may affect results.
55 citations
,
March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
May 2015 in “Evidence Based Women Health Journal (Online)” Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.
66 citations
,
October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.
May 2024 in “Journal of drug delivery and therapeutics” Women with PCOS have higher oxidative stress and hormone imbalances, suggesting managing oxidative stress could help.
108 citations
,
January 2010 in “International Journal of Andrology” Weak endocrine disruptors in mixtures can have significant effects and should be considered in risk assessments.
Neurosteroids help control dopamine responses in the brain.
1 citations
,
February 2013 in “Steroids” Bone mineral and minocycline boost bone cell growth, aiding healing.
37 citations
,
September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
4 citations
,
September 2011 in “American Journal of Clinical Dermatology” Ethinylestradiol/chlormadinone acetate may be an effective and well-tolerated treatment for skin conditions caused by excess androgens.
40 citations
,
March 2014 in “Journal of Family Planning and Reproductive Health Care” PCOS is a common hormonal disorder in women, marked by high androgen levels and often seen in 20% of women via ultrasound.
8 citations
,
April 2020 in “Journal of The American Academy of Dermatology” Bicalutamide may be a promising alternative treatment for female pattern hair loss.
November 1978 in “PubMed” Antiandrogenic treatments can effectively manage certain skin conditions by using female hormones.
May 1993 in “Drugs & Therapy Perspectives” Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
June 2023 in “Oriental Journal of Chemistry/Oriental journal of chemistry” New compounds may help treat prostate cancer by reducing cell growth.
108 citations
,
January 2003 in “Fertility and Sterility” Flutamide may slightly improve hair loss in women, but finasteride does not work.
October 2025 in “CRC Press eBooks” 14 citations
,
September 2023 in “Frontiers in Nutrition” Pro-, pre-, and synbiotics may help with PCOS, but more research is needed.
October 2004 in “Australian Prescriber” Lifestyle changes are more effective than metformin for reducing type 2 diabetes risk.
August 2013 in “Fertility and Sterility” High levels of fatty acids are linked to increased androgen production and inflammation in women with PCOS, which may affect IVF outcomes.
57 citations
,
April 2009 in “The Journal of Steroid Biochemistry and Molecular Biology” Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
17 citations
,
January 1986 in “Acta obstetricia et gynecologica Scandinavica” Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.