research The Use of Anabolic Steroids by Bodybuilders in the State of Sergipe, Brazil
Many bodybuilders in Sergipe, Brazil use anabolic steroids, facing health risks like acne, irritability, and hypertension.
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research Comparison of minoxidil sulfotransferase activity between scalp hair, eyebrows, and eyelashes: Implication for minoxidil efficacy for off‐label use
Minoxidil is less effective on eyebrows and eyelashes than scalp hair because these areas have lower enzyme activity needed to activate the drug.
research A scientometric study on research trends and characteristics of discoid lupus erythematosus
Effective treatments for discoid lupus erythematosus are needed, as current options are unsatisfactory and off-label.
research 13777 The off-label use of spironolactone in female pattern hair loss
GSK-36 downregulation with UTMD improves plaque stability in atherosclerosis treatment.
research How to Select Pharmacologic Treatments to Manage Recidivism Risk in Sex Offenders: Consider Patient Factors When Choosing Off-Label Hormonal and Nonhormonal Agents
Choose treatments for sex offenders based on individual needs, using hormonal and nonhormonal options to reduce sexual drive.
research 448 Challenges of securing insurance approval for oral tofacitinib treatment of alopecia areata: A multi-institutional retrospective review
Getting insurance to cover the hair loss treatment tofacitinib is hard because it's not officially approved for that use.
research Mixing the Old with the New: Drug Repurposing for Immune Deficiency in the Era of Precision Medicine and Pediatric Genomics
Using old drugs for new uses can help treat rare immune deficiencies.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Economic Burden of Alopecia Areata in the Kingdom of Saudi Arabia from a Societal Perspective: A Cost-of-Illness Analysis
Alopecia areata in Saudi Arabia is costly, mainly due to lost productivity and drug costs.
research Hair Are the Rankings—5-α Reductase Inhibitors and Minoxidil in Male Androgenetic Alopecia
Minoxidil and finasteride are FDA-approved treatments for male hair loss, but off-label use of oral minoxidil, dutasteride, and higher doses of finasteride and minoxidil is increasing.
research Dupilumab in a 9-week-old with Netherton Syndrome Leads to Deep Symptom Control
Dupilumab effectively controls symptoms in infants with Netherton syndrome.
research Metformin potential in predisposing arthralgia, type II cross reactivity secondary to group A streptococcus infection & other comorbidities in treating PCOS
The document discussed the treatment of Polycystic Ovarian Syndrome (PCOS) in adolescents using metformin, an oral antidiabetic drug, and hormone replacement therapy. While metformin was effective in treating PCOS, its off-label use was controversial due to potential side effects, including back pain, swollen joints, and rare behavioral changes. The document presented a case of a female with PCOS who, after more than two years of metformin treatment, experienced hyperuricemia, migraines, neurological pain, severe joint pain, and rheumatic fever. Treatment for rheumatic fever with benzathine benzyl penicillin led to a Type IV delayed hypersensitivity reaction, highlighting the complexities and risks associated with treating PCOS with metformin and subsequent treatments.
research Hypersensitivity to intravenous ondansetron: a case report
Ondansetron can cause serious allergic reactions, so use it carefully.
research Management of folliculitis decalvans: The EADV task force on hair diseases position statement
Control inflammation and prevent further hair loss in folliculitis decalvans using medications and therapies.
research Farmácia Lusitana, Vila do Conde e nos Serviços Farmacêuticos do Hospital CUF, Porto
Pharmacists play a crucial role in improving treatment outcomes and staying updated on various health conditions.
research Alopecia universalis successfully treated with tofacitinib
Tofacitinib helped a 19-year-old regrow hair after other treatments failed.
research Treatments for Moderate-to-Severe Alopecia Areata: A Systematic Narrative Review
Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.
research A Case of Tofacitinib for the Treatment of Resistant Vitiligo and Sustained Repigmentation After Discontinuation
A woman's vitiligo improved with tofacitinib treatment, and her skin color remained even after stopping the medication, but there are concerns about cancer risk.
research Off-Label Uses of Topical Vitamin D in Dermatology: A Systematic Review
Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.
research Off-label use of biologics and janus kinase (JAK) inhibitors for scarring alopecias: a narrative review
Biologics and JAK inhibitors may improve treatment for scarring alopecias.
research Botulinum Toxin Off-Label Use in Dermatology: A Review
Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
research Off-Label Use of Botulinum Toxin in Dermatology—Current State of the Art
Botulinum toxin is effective for various skin conditions, but more research and awareness of side effects are needed.
research Off-Label Uses of Abrocitinib: Review of Emerging Therapeutic Applications beyond Atopic Dermatitis
Abrocitinib shows promise for treating various skin conditions beyond atopic dermatitis.
research Off-label uses of retinoids in dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Beyond Minoxidil: Evidence-Based Off-Label Therapies for Male Androgenetic Alopecia
Some off-label treatments may be effective for male pattern baldness.
research Facial hair enhancement with minoxidil—an off-label use
Minoxidil can help increase facial hair growth.
research Review of Promising Off-Label Use of Deucravacitinib
Deucravacitinib may help treat various immune diseases beyond psoriasis, but more research is needed.
research Alopecia Areata: The Clinical Situation
Treating alopecia areata is difficult due to limited approved treatments, but new therapies like JAK inhibitors show promise.
research Cicatricial alopecia
Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
research Real-world pharmacovigilance insights into drug-induced risk of alopecia
64 drugs can cause hair loss, needing better monitoring and updated labels.