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Critical Analysis on Characterization, Systemic Effect, and Therapeutic Potential of Beta-Sitosterol: A Plant-Derived Orphan Phytosterol

research Critical Analysis on Characterization, Systemic Effect, and Therapeutic Potential of Beta-Sitosterol: A Plant-Derived Orphan Phytosterol

75 citations , November 2016 in “Medicines”

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

research 5α-Reductases In Human Physiology: an Unfolding Story

44 citations , July 2012 in “Endocrine Practice”

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

research In silico analysis of ethyl acetate Bruguiera gymnorhiza leaf extracts as an anti-inflammatory agent

4 citations , September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia”

Bruguiera gymnorhiza leaf extracts show potential for developing anti-inflammatory drugs.

research 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine

19 citations , June 2010 in “Journal of acupuncture and meridian studies”

A plant extract was found to effectively block an enzyme related to male hormone-related diseases.

research Table 1_Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques.xlsx

May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Jamogenin and other molecules from plants may help treat hair loss.

Baseline Distribution of Eyebrow and Eyelash Loss by Severity of Scalp Hair Loss in Phase 3 Trials of Baricitinib for Alopecia Areata

research 41247 Baseline distribution of eyebrow and eyelash loss by severity of scalp hair loss in phase 3 trials of baricitinib for alopecia areata

September 2023 in “Journal of The American Academy of Dermatology”

The document's conclusion cannot be provided because the content is not available.

research Biochemical and histological effects of feeding thermally oxidized rapeseed oil and lard to rats.

33 citations , January 1977 in “PubMed”

Feeding rats oxidized rapeseed oil and lard caused weight loss, organ damage, and toxicity symptoms.

research Synthesis, Anticancer and Molecular Docking Studies of 2-(4-chlorophenyl)-5-aryl-1,3,4-Oxadiazole Analogues

8 citations , January 2013 in “Medicinal chemistry”

The compound 4c showed strong potential as an anticancer agent.

research Formulation and test activities of hair tonic with a combination of the aqueous extracts of aloe vera ( Aloe vera L.) and licorice (Glycyrrhiza glabra L.)

1 citations , June 2018 in “Pharmaciana”

The hair tonic with 15% ethanol effectively promotes hair growth.

research Studies of the components of an oral contraceptive agent in albino rats. II. Progestogenic component and comparison of effects of the components and the combined agent

24 citations , July 1980 in “Journal of Toxicology and Environmental Health”

High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.

research Simultaneous determination of seven prohibited substances in cosmetic products by liquid chromatography–tandem mass spectrometry

13 citations , April 2013 in “Chinese Chemical Letters/Chinese chemical letters”

The method effectively identifies and measures seven banned substances in cosmetics.

Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 from Relevant Ethno-Pharmacological Plants via In Silico Techniques

research Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 Inhibitors from Relevant Ethno-pharmacological Plants via In Silico Techniques

May 2024 in “Scientific African”

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

research In vitro [7-3H]-testosterone metabolism by the rat ventral prostate—Effect of some exogenous compounds

12 citations , February 1975 in “Journal of Steroid Biochemistry”

research Enhanced Skin Permeation and Controlled Release of β-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia

5 citations , April 2023 in “Pharmaceuticals”

The new delivery system improved hair growth in alopecia treatment.

Mechanisms of Disease: Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Novel Treatment for Metabolic Syndrome

research Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome

69 citations , December 2005 in “Nature Clinical Practice Endocrinology & Metabolism”

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

research Anti-androgenic potential of the fruit extracts of certain Egyptian Sabal species and their genetic variability studies: a metabolomic-molecular modeling approach

1 citations , January 2022 in “Food & Function”

Certain Egyptian Sabal fruit extracts may help treat anti-androgenic diseases like benign prostatic hyperplasia.

research Effects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia

16 citations , January 2019 in “Pharmaceutical biology”

Lespedeza cuneata extract may help treat enlarged prostate.

Using MALDI-MSI Analysis to Study Distribution of FOL-005, a Potent, Novel Inhibitor of Human Hair Growth, After Subcutaneous Injection in Mice

research 695 Using MALDI-MSI analysis to study distribution of FOL-005, a potent, novel inhibitor of human hair growth, after subcutaneous injection in mice

April 2016 in “Journal of Investigative Dermatology”

FOL-005, a new substance, was found to reduce hair growth without toxicity when injected into skin, suggesting it could be used to treat excessive hair growth.

Compatibility of Caffeine, Clobetasol Propionate, Dutasteride, Nicotinamide, and Progesterone in TrichoFoam, a Natural Vehicle for Hair Foams

research Compatibility of Caffeine Clobetasol Propionate Dutasteride Nicotinamide and Progesterone in TrichoFoam™, a Natural Vehicle for Hair Foams.

April 2024 in “PubMed”

TrichoFoam™ is a stable option for personalized hair loss treatment with most ingredients remaining effective for 90-180 days.

research N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase

17 citations , December 2004 in “Bioorganic & Medicinal Chemistry Letters”

Scientists found new, better-working inhibitors for a hormone-related enzyme.

research Reduced estradiol synthesis by letrozole, an aromatase inhibitor, is protective against development of pentylenetetrazole-induced kindling in mice

14 citations , October 2015 in “Neurochemistry International”

Letrozole may help prevent seizures by reducing certain hormone levels.

A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia

research A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-α-Reductase in the Treatment of Androgenetic Alopecia

65 citations , April 2002 in “Journal of Alternative and Complementary Medicine”

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

research HAIR TONIC OF BROCCOLI (BRASSICA OLERACEA VAR. ITALICA) EXTRACT: FORMULATION, PHYSICAL CHARACTERISTIC, STABILITY AND HAIR GROWTH ACTIVITY TEST

2 citations , August 2024 in “International Journal of Applied Pharmaceutics”

Broccoli extract hair tonic effectively promotes hair growth and is safe to use.

research FORMULATION AND EVALUATION OF POLYHERBAL HAIR OIL

June 2023 in “Zenodo (CERN European Organization for Nuclear Research)”

The herbal hair oil promotes excellent hair growth and is a safer alternative to synthetic oils.

research 5α-Reductase inhibitors in androgenetic alopecia

January 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity”

Inhibition of Prolactin Promotes Secondary Skin Follicle Activation in Cashmere Goats

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