research AnnoPharma: Detection of substances responsible of ADR by annotating and extracting information from MEDLINE abstracts
AnnoPharma effectively identifies substances causing adverse drug reactions in medical abstracts.
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210-240 / 1000+ results research Ocfentanil testing in hair from a fatality case: Comparative analysis of a lock of hair versus a single hair fiber
Both a lock of hair and a single hair strand can show chronic drug use, but at least six single hairs are needed for accurate results.
research Transcriptome profiling of whisker follicles in methamphetamine self-administered rats
Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.
research Relating neurosteroid modulation of inhibitory neurotransmission to behaviour
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Inhibiting Biosynthesis and/or Metabolism of Progestins in the Ventral Tegmental Area Attenuates Lordosis of Rats in Behavioural Oestrus
Blocking certain brain processes reduces mating behavior in female rats.
research Bound on the Risk for M-SVMs
The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.
research Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice
GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.
research The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research S1 OPIOID RECEPTOR AGONISTS AND SERUM PROSTATE SPECIFIC ANTIGENE LEVEL: IS THERE A ROLE FOR PROSTATE CANCER CONTROL AND CHEMOPREVENTION?
Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.
research Walrus
Anesthetizing walruses is difficult and risky due to their size and sudden health changes.
research SUBSTYTUCJA EGZOGENNYCH CHOLINESTERAZ W LECZENIU CIĘŻKICH ZATRUĆ ZWIĄZKAMI FOSFOROORGANICZNYMI
Combining standard treatment with exogenous cholinesterases can improve outcomes in severe organophosphate poisoning.
research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
research Regulation of itch-induced scratching by nucleus accumbens dopamine receptor-expressing neurons
Dopamine receptors in the brain influence itch-related scratching behavior.
research Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-derived Peptides in Murine Skin
POMC-derived peptides are important for skin functions like immune response and stress management.
research Pharmacophore Models for Toxicology Prediction
Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.
research ABSTRACTS—SYMPOSIA
Certain drugs can block changes in brain receptors caused by alcohol withdrawal.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research Hair analysis for monitoring drug use
Hair analysis can effectively monitor long-term drug use.
research Oil-in-Water型ナノエマルションに基づく局所経皮送達システムに関する研究
The nanoemulsion system effectively delivers drugs through the skin and shows promise for treating skin conditions.
research S2 PSA: RELIABLE OR NOT RELIABLE?
PSA testing is a reliable method for detecting prostate cancer, and opioids may lower PSA levels, but triglycerides don't affect prostate cancer risk.
research NIEFARMAKOLOGICZNA METODA REDUKCJI BÓLU FIZYCZNEGO POPRZEZ ZMIANĘ RODZAJU UWAGI. OPIS PRZYPADKÓW I METODY
Shifting attention can reduce physical pain.
research DRUGS OF ABUSE | Hair
research [Candida folliculitis in heroin addicts. Histological study].
Candida was found in most heroin users with folliculitis.
research Presumed ocular candidiasis in drug misusers after intravenous use of oral high dose buprenorphine (Subutex)
Drug misuse can cause serious eye infections and other severe side effects.
research Procyanidins attenuate neuropathic pain by suppressing matrix metalloproteinase-9/2
Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
research In vivo Assessment of the Antinociceptive Activity of Ethanol Bark Extract of Thevetia peruviana (Family: Apocynaceae) in Swiss Albino Mice
Thevetia peruviana bark extract reduces pain in mice and may help create new painkillers.
research Dimensions of drug information
A new method organizes drug information to improve data use and create a comprehensive drug database.
research Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats
Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.
research Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research 50285 Oxytocin receptor is present in keratinocytes near touch and pain sensory neurons
Oxytocin receptors are found in skin cells near touch and pain neurons.