research Industry update: the latest developments in the field of therapeutic delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
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research Clinical efficacy of silk sericin dressing with collagen for split-thickness skin graft donor site treatment
Silk sericin dressing with collagen heals wounds faster and improves scar quality better than Bactigras.
research اثر تستوسترون اگزوژن و داروی Finasteride بر بی دردی ناشی از مورفین در موش های سوری نر با استفاده از تست فرمالین
Testosterone reduces, while finasteride enhances, morphine's pain relief.
research 0557 Possible Contributory and Protective Factors in Medication Associated Obstructive Sleep Apnea (OSA): Results from the US Food and Drug Administration (FDA) Adverse Events Reporting System (FAERS)
Some drugs may increase the risk of obstructive sleep apnea, while others like certain biologics might decrease it.
research Index
The document is a detailed guide on skin conditions and treatments for dermatologists.
research Complex Regional Pain Syndrome Type I : measurements and treatment
CRPS I is complex, linked to immune and nerve issues, and needs comprehensive treatment.
research Polycystic ovary syndrome and impact on health
PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
research 41495 Efficacy of Oral Naltrexone in the Treatment of Scarring Alopecia
Low-dose oral naltrexone may help reduce inflammation in some scarring alopecia patients.
research Effects of Curcumin and Its Different Formulations in Preclinical and Clinical Studies of Peripheral Neuropathic and Postoperative Pain: A Comprehensive Review
Curcumin shows promise in reducing pain and inflammation, but more research is needed.
research A Soy-Derived Immunostimulating Peptide Inhibits Etoposide-Induced Alopecia in Neonatal Rats
Soymetide-4 from soy can prevent hair loss caused by a cancer drug in rats.
research Neuroendocrine Determinants of Polycystic Ovary Syndrome
Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.
research Finasteride, a 5alpha-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat
Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
research The Therapeutic Potential of Cannabidiol in Skin Conditions
CBD might help with skin issues, but more research is needed.
research Editor's Picks August 2023
Anti-IL17A therapy reduced venous leg ulcer size by 64% without major side effects.
research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines
The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.
research Chemistry, Pharmacology and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research The use of anabolic androgenic steroids: A focus on polypharmacy
Using high doses and multiple drugs with steroids is risky and should be prevented.
research Sensory and physiological dimensions of cold pressor pain in trichotillomania
Adults with trichotillomania do not have different pain sensitivity to cold pressor pain compared to healthy individuals.
research New developments in our understanding of acne pathogenesis and treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes
CRH promotes fat production in skin cells, affecting conditions like acne.
research Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.
research 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis
LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.
research Dupilumab in Inflammatory Skin Diseases: A Systematic Review
Dupilumab effectively treats various inflammatory skin diseases beyond its initial use for atopic dermatitis.
research Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice
Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
research Membrane androgen receptors may mediate androgen reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features
The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.
research Trichotillomania: What Do We Know So Far?
Trichotillomania treatment is most successful with a mix of behavioral therapy, medication, and social support.
research Trichotillomania as a Manifestation of Dementia
Trichotillomania in dementia may be better treated with dopamine blockers like quetiapine than with SSRIs.
research Knowledge Mapping of Drug Repositioning’s Theme and Development
Drug repositioning can save time and money but needs more support.
research Management of psychiatric disorders with HIV and dermatological disorders
The conclusion is that careful management of both psychiatric and skin conditions is crucial for HIV patients, using medication and interdisciplinary approaches.