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Exploring the Factors to Regulate Sweating by Transcriptome Analysis for Anhidrosis: Novel Role of Olfactory Receptors on Sweating via Exposing to Beta-Ionone

research 1377 Exploring the factors to regulate sweating by transcriptome analysis for anhidrosis: Novel role of olfactory receptors on sweating via exposing to β-ionone

April 2023 in “Journal of Investigative Dermatology”

Sweating can potentially be controlled through olfactory receptors, with β-ionone playing a key role, and responses may vary between genders.

Functional Characterization of OR51B5 and OR1G1 in Human Lung Epithelial Cells as Potential Drug Targets for Non-Type 2 Lung Diseases

research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases

4 citations , November 2024 in “Cell Biology and Toxicology”

Blocking certain receptors in the lungs might help treat a specific type of asthma.

research Olfactory receptor OR2AT4 regulates human hair growth

82 citations , September 2018 in “Nature Communications”

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

research Prostate cancer risk and recurrence: the role of nutrition and clinical aspects

January 2013

Higher cholesterol levels increase aggressive prostate cancer risk.

research 10.1063/5.0132123.1

February 2023 in “Default Digital Object Group”

Appendix A: Mathematical Model AL/RC/ASE. Functional Androgen Axis (FOA) - Operational Version v1.2

research Dodatek A: Model matematyczny AL/RC/ASE. Functional Androgen Axis (FOA) - wersja operacyjna v1.2

April 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

The model improves understanding of androgen interactions by focusing on signal intensity and system capacity.

research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route

3 citations , October 1994 in “Journal of Labelled Compounds and Radiopharmaceuticals”

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Increased Expression of Ectodysplasin A2 Receptor EDA2R Is the Most Remarkable and Ubiquitous Aging-Related Transcriptional Hallmark

research Increased expression of Ectodysplasin A2 Receptor EDA2R is the most remarkable and ubiquitous aging-related transcriptional hallmark

3 citations , August 2021 in “Research Square (Research Square)”

The most common sign of aging at the gene level is more Ectodysplasin A2 Receptor (EDA2R) being made.

research Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71 rco12 and Krt71 rco13

51 citations , December 2006 in “Mammalian Genome”

research The Percentage of Free PSA and Urinary Markers Distinguish Prostate Cancer from Benign Hyperplasia and Contribute to a More Accurate Indication for Prostate Biopsy

11 citations , June 2020 in “Biomedicines”

% free PSA and urinary markers help better identify prostate cancer.

research Targeting olfactory receptor OR2AT4: An innovative aptamer-based treatment for hair growth promotion

June 2025 in “Molecular Therapy — Nucleic Acids”

A new treatment using a DNA aptamer can promote hair growth by targeting a specific receptor.

research Ectopic olfactory receptors in human: New therapeutic possibilities

May 2020 in “Authorea (Authorea)”

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

research Fast Motions in 5 Alpha Reductase and Its Impact on Enzyme Kinetics

May 2026 in “ACS Catalysis”

The study investigates the catalytic mechanism of steroid 5α-reductase type 2 (SRD5A2), focusing on the dynamic interactions among residues that affect enzyme kinetics. Using QM/MM simulations, it was found that residues Tyr33 and L224 compress the donor, altering free energy barriers and supporting the preorganization theory. Additionally, six other residues (Trp53, Arg94, Cys119, Glu197, Phe223, and Arg227) form a network that stabilizes transition states through electrostatic and structural interactions. The L224P mutant analysis shows that losing L224 compression increases energy barriers by 3.3-3.4 kcal/mol, highlighting the importance of dynamic and electrostatic coordination for efficient catalysis.