July 2022 in “Journal of Investigative Dermatology” Substance P may contribute to hair loss by increasing oxidative stress and mitochondrial activity in hair follicles.
46 citations
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December 1992 in “Journal of Investigative Dermatology” Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.
49 citations
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October 1989 in “Genomics” Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.
68 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
79 citations
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January 1999 in “Dermatologic surgery” Different skin treatments work best for different levels of wrinkles and sun damage.
6 citations
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April 2017 in “Journal of Dermatological Science” Ovariectomized mice mimic postmenopausal hair loss, and estradiol helps maintain hair density.
13 citations
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January 1987 in “Dermatology” Minoxidil sulfate relaxes blood vessels by increasing potassium permeability.
The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.
21 citations
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December 2001 in “Endocrinology” Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.
10 citations
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June 2005 in “Small ruminant research” Melatonin treatment may increase cashmere production in Spanish goats.
63 citations
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January 2010 in “Frontiers in Aging Neuroscience” 3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
1 citations
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December 2024 in “Journal of Orthopaedic Research®” Aromoline and DRD4 are potential targets for osteoarthritis treatment.
9 citations
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March 2019 in “Scientific reports” Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
March 2026 in “Molecular and Cellular Biomedical Sciences” EH-MSCs may help treat hair loss by reducing inflammation.
1 citations
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April 2015 in “The FASEB Journal” Blocking androgens in male rats increased estrogen and made them more active.
8 citations
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April 2021 in “Journal of Clinical Investigation” Finasteride reduces opioid use and withdrawal symptoms in animals.
74 citations
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October 2015 in “Experimental Dermatology” Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.
December 2025 in “npj Systems Biology and Applications” Cold temperatures can stop human cell circadian rhythms, but warming restores them.
9 citations
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January 2016 in “Skin Pharmacology and Physiology” The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
9 citations
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August 2019 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil activation by hair enzymes predicts treatment success for female hair loss.
5 citations
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February 2019 in “Neuroscience letters” Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
10 citations
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March 2019 in “Journal of neuroendocrinology” Testosterone affects stress hormone levels differently in adolescent and adult male rats.
7 citations
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December 2008 in “Journal of Dermatological Science” Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.
January 2022 in “Figshare” Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.
5 citations
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December 2015 in “Dermatologic Therapy” Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.
2 citations
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April 2024 in “Molecular Plant” Auxin promotes root hair growth through oxidative processes involving reactive oxygen species.
Male goat smell increases reaction in young female goats' noses but doesn't cause them to start puberty early.
13 citations
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January 2021 in “Scientific Reports” Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
May 2018 in “KU ScholarWorks (The University of Kansas)” Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.