research K channel therapeutics at the bedside
Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
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research The influence of methotrexate on hair loss while using immunomodulatory doses.
Methotrexate treatment often causes hair loss.
research Adverse Health Effects of Selenium in Humans
High selenium exposure can harm thyroid function, immune system, liver, skin, and may increase neurotoxicity and cancer risk.
research 원저 : 원형탈모증의 cyclosporine 병합치료
Cyclosporine combined with other treatments can help hair regrow in severe alopecia areata, but it may cause side effects.
research Proliferative necrotizing otitis externa in two young cats
Two young cats with a severe ear and skin condition improved with immune system-targeting treatments.
research Safety profile of CAP7.1 obtained during Phase I Trial in adult patients with refractory malignancies
CAP7.1 is generally safe at 200 mg/m²/day, but can cause fatigue, nausea, hair loss, fever, and blood-related issues.
research The investigation of minoxidil-induced [Ca2+]irises and non-Ca2+-triggered cell death in PC3 human prostate cancer cells
Minoxidil increases calcium levels and kills prostate cancer cells independently of calcium.
research Pharmacological evidence for the involvement of adenosine triphosphate sensitive potassium channels in chloroquine-induced itch in mice
ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.
research Faculty Opinions recommendation of Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.
Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.
research ACOD1 deficiency promotes DDX1 methylation–mediated mitochondrial dysfunction and dermal papilla cell senescence in androgenetic alopecia
This study investigates the role of ACOD1 in androgenetic alopecia (AGA), highlighting its impact on dermal papilla cell (DPC) senescence. The research shows that ACOD1 deficiency leads to increased DDX1 methylation, resulting in mitochondrial dysfunction and DPC senescence, which are key factors in AGA pathogenesis. The study utilized various methods, including RNA sequencing and metabolomic analysis, to demonstrate that ACOD1 knockdown exacerbates mitochondrial issues and cellular aging, while its overexpression mitigates these effects. Additionally, the study found that exogenous 4-octyl itaconate (4-OI) supplementation can reduce DDX1 methylation, improve mitochondrial function, enhance cell proliferation, and reduce hair loss in AGA mice. These findings suggest that targeting ACOD1 and using 4-OI could be promising therapeutic strategies for treating AGA.
research Vorasidenib-Induced Trichomegaly and Hypertrichosis: a New Side Effect in a Patient with Diffuse Astrocytoma
Vorasidenib can cause unusual hair growth.
research Epidermal Growth Factor Upregulates Production of Supernumerary Hair Cells in Neonatal Rat Organ of Corti Explants
Epidermal growth factor increases extra hair cells in newborn rat ears.
research Mild oxidative stress protects against chemotherapy-induced hair loss
Mild oxidative stress can prevent hair loss from chemotherapy.
research MALEFÍCIOS PROVOCADOS POR SUBSTÂNCIAS ALCALINAS NO COURO E HASTE CAPILAR
Este estudo revisou os danos causados por substâncias alcalinas de alto pH no cabelo, destacando que o uso de agentes químicos para alisamento pode causar intumescimento das fibras capilares e degradação proteica devido à abertura das escamas cuticulares. O uso de hidróxidos metálicos pode levar à lantionização, enfraquecendo irreversivelmente a resistência do cabelo. Além disso, o pH elevado neutraliza o manto ácido do couro cabeludo, aumentando o risco de dermatites, queimaduras químicas e alopecias cicatriciais irreversíveis. A conclusão enfatiza a necessidade de priorizar a saúde capilar e educar sobre os riscos associados a esses procedimentos.
research Methotrexate Effectively Controls Ocular Inflammation in Japanese Patients With Non-infectious Uveitis
Methotrexate effectively controls eye inflammation in Japanese patients with non-infectious uveitis but requires careful monitoring for side effects.
research Demethylation of ITGAV accelerates osteogenic differentiation in a blast-induced heterotopic ossification in vitro cell culture model
Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
research THU0239 Methotrexate Dose has Minimal Effects on Methotrexate-Related Toxicity in Patients with Early Rheumatoid Arthritis Treated in Combination with Adalimumab – Results of Concerto Trial
Methotrexate dose has little effect on its toxicity when used with adalimumab for early rheumatoid arthritis.
research The effects of acute finasteride treatment in dopamine transporter knockout mice and MK-801-treated mice
research Hair Loss Induced by Tumor Necrosis Factor Alpha Inhibitors
Some drugs used to treat immune conditions may cause different types of hair loss.
research Vitamins
Taking too much vitamin A can cause health problems like bone pain and hair loss.
research Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort
Fluconazole can cause hair loss, but the exact cause is unknown.
research 69 Risk-benefit appraisal of systemic JAK inhibitors for alopecia areata: a comprehensive meta-analysis assessing safety and adverse effects
JAK inhibitors are effective and generally safe for treating alopecia areata, but monitoring for side effects is important.
research Patients with bullous skin disease in a high‐epidemic COVID‐19 area, Bergamo, Italy
Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.
research Minoxidil oral a altas dosis para el tratamiento de la alopecia androgenética
High-dose oral minoxidil can improve hair growth but may cause side effects.
research High-risk cutaneous squamous cell carcinoma in a Japanese allogeneic bone marrow transplant recipient on long-term voriconazole
A Japanese bone marrow transplant patient developed a rare skin cancer possibly linked to long-term use of the medication voriconazole.
research Severe and refractory hypotension after intentional minoxidil overdose: a case report
Minoxidil overdose caused severe low blood pressure, but the patient recovered with specific treatments.
research Minoxidil and pericardial effusion: An idiosyncratic reaction
Minoxidil can cause dangerous fluid buildup around the heart.
research A Case of Inflammatory Nonscarring Alopecia Associated With the Tyrosine Kinase Inhibitor Nilotinib
A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.
research 원저 : 탈모증 환자에서 미녹시딜 용액 사용 실태에 관한 이메일 설문 조사
Proper guidance on minoxidil use and side effects is crucial.
research Inhibitory effect of tianeptine on catagen induction in alopecia areata-like lesions induced by ultrasonic wave stress in mice
Tianeptine, an antidepressant, may prevent stress-induced hair loss in mice.