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Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators in Differentiation, Proliferation, and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

research Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators Involving in Differentiation, Proliferation and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

January 2023 in “Frontiers in bioscience”

Artemis protein may help control hair growth and health by influencing cell processes.

research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models

5 citations , August 2019 in “iScience”

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

research Expression patterns of programmed cell death 4 protein in normal human skin and some representative skin lesions

37 citations , February 2007 in “Experimental Dermatology”

Increasing PDCD4 protein may help prevent or treat some skin cancers.

research Itpr3 Is Responsible for the Mouse Tufted (tf) Locus

6 citations , October 2012 in “Journal of Heredity”

The Itpr3 gene causes a specific hair pattern in mice.

research miR-22 promotes stem cell traits via activating Wnt/β-catenin signaling in cutaneous squamous cell carcinoma

30 citations , August 2021 in “Oncogene”

miR-22 helps skin cancer grow and spread by activating specific cell signals.

research Ber‐EP4 antigen is a marker for a cell population related to the secondary hair germ

21 citations , June 2004 in “Experimental Dermatology”

Ber‐EP4 marks cells related to the secondary hair germ in hair follicles.

research p53 Involvement in the Control of Murine Hair Follicle Regression

71 citations , June 2001 in “American Journal of Pathology”

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

research p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis

166 citations , September 2011 in “The Journal of Cell Biology”

p63 controls Satb1 to help skin develop properly.

research KIF18B is a cell-type specific regulator of spindle orientation in the epidermis

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

research MAD2B acts as a negative regulatory partner of TCF4 on proliferation in human dermal papilla cells

8 citations , September 2017 in “Scientific Reports”

MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.

research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

380 citations , March 2000 in “Proceedings of the National Academy of Sciences”

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

research Building Models for Keratin Disorders

4 citations , April 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

Krt16-deficient mice help understand skin disorders like PC and FNEPPK.

research A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration

September 2016 in “Journal of Dermatological Science”

The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.

research Congenital atrichia with papular lesions resulting from novel mutations in human hairless gene in four consanguineous families

11 citations , February 2011 in “The Journal of Dermatology”

Mutations in the hairless gene cause a rare form of permanent hair loss.

research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

6 citations , December 2019 in “Frontiers in genetics”

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

research The use of polyethylenimine–DNA to topically deliver hTERT to promote hair growth

17 citations , May 2011 in “Gene Therapy”

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

Characteristics of KRT80 and Its Roles in Neoplastic Diseases

research Characters of KRT80 and its roles in neoplasms diseases

2 citations , May 2023 in “Cancer medicine”

KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.

research KRT72 wt Allele

February 2020 in “Definitions”

KRT72 gene helps form hair.

research HIF‐2α/ARNT complex regulates hair development via induction of p21 ^Waf1/Cip1 and p27 ^Kip1

4 citations , March 2014 in “The FASEB Journal”

The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.

research An ultrahigh-sulphur keratin gene of the human hair cuticle is located at 11q13 and cross-hybridizes with sequences at 11p15

15 citations , January 1991 in “Mammalian Genome”

research A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3

34 citations , January 2004 in “Genomics”

A cluster of 21 keratin-associated protein genes important for hair growth was found on human chromosome 21.

research Indian Hedgehog Controls Proliferation and Differentiation in Skin Tumorigenesis and Protects against Malignant Progression

15 citations , July 2013 in “Cell Reports”

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

research Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA‐1 expression

47 citations , February 2014 in “Journal of Cutaneous Pathology”

Matrical tumors share a common growth mechanism involving the Wnt pathway and consistent PHLDA1 expression.

research A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions

47 citations , April 2000 in “Experimental Dermatology”

A new gene mutation causes a rare type of hair loss.

research P63 expression pattern during rat epidermis morphogenesis and the role of p63 as a marker for epidermal stem cells

16 citations , September 2006 in “Journal of Cutaneous Pathology”

P63 is a marker for epidermal stem cells in rats.

research A Group of Type I Keratin Genes on Human Chromosome 17: Characterization and Expression

38 citations , February 1988 in “Molecular and Cellular Biology”

Only one of the two K16 genes on chromosome 17 makes a functional protein for keratin filaments.

research 0748 Synergy of TP53 and non-canonical sonic hedgehog pathway in the development of complex basal cell carcinoma

July 2025 in “Journal of Investigative Dermatology”

Complex basal cell carcinomas need personalized treatment due to unique genetic mutations.

A New Way to Restore Tumor Suppressor Function

research A new way to restore tumour suppressor function

August 2013 in “Nature Reviews Drug Discovery”

New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.

research Chaperones as thermodynamic sensors

August 2013 in “Nature Reviews Drug Discovery”

New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

research Keratins 6, 16, and 17 in Health and Disease: A Summary of Recent Findings

37 citations , August 2024 in “Current Issues in Molecular Biology”

Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.

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