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Prostaglandin E2 Prevents Radiotherapy-Induced Alopecia by Attenuating Transit Amplifying Cell Apoptosis Through Promoting G1 Arrest

research 1503 Prostaglandin E2 prevents radiotherapy-induced alopecia by attenuating transit amplifying cell apoptosis through promoting G1 arrest

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.

research 5α-Reductase: History and Clinical Importance

20 citations , January 2004 in “PubMed Central”

5α-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT levels.

research Potassium channel openers: pharmacological and clinical aspects

119 citations , October 1992 in “Fundamental & Clinical Pharmacology”

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances

153 citations , November 2004 in “Current Medicinal Chemistry”

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

research ポ-トフォリオを使った社会科教育法の授業実践--ポ-トフォリオによるカリキュラム改革と教師の力量形成(2)

December 1998 in “福井大学教育学部紀要第4部教育科学”

HA-P5 effectively treats acne without causing side effects seen in other treatments.

research Bioassay-guided isolation of two antiproliferative metabolites from Pterocarpus indicus Willd. against TGF-β-induced prostate stromal cells (WPMY-1) proliferation via PI3K/AKT signaling pathway

3 citations , October 2024 in “Frontiers in Pharmacology”

Compounds from Pterocarpus indicus may help treat benign prostatic hyperplasia by stopping cell growth.

research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases

51 citations , May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Certain drugs that block specific enzymes can help treat prostate diseases.

research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases

11 citations , February 2016 in “Current Medicinal Chemistry”

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

research Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis

8 citations , July 2024 in “Journal of Advanced Research”

CDK inhibitors may help treat ARDS and psoriasis but need more testing for safety and effectiveness.

research Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain

24 citations , December 2011 in “International Journal of Cancer”

PTH-CBD agonists may help regrow hair after chemotherapy.

Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia

research Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia

May 2024 in “Nano letters”

Polydopamine and quercetin together can speed up hair regrowth.

research Progestogens with Antiandrogenic Properties

164 citations , January 2003 in “Drugs”

research Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis

19 citations , October 2018 in “PLOS ONE”

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Pharmacological Activity and Clinical Use of Polydeoxyribonucleotide

research Pharmacological Activity and Clinical Use of PDRN

80 citations , April 2017 in “Frontiers in Pharmacology”

PDRN helps repair tissue and improve wound healing with a high safety profile.

research Polynucleotides in aesthetic medicine: the science, mechanisms and clinical considerations

January 2026 in “Journal of Aesthetic Nursing”

Polynucleotides improve skin quality and are safe and effective for rejuvenation.

Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3

research Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3

15 citations , April 2008 in “Steroids”

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

research Parathyroid hormone-related peptide and the hair cycle - is it the agonists or the antagonists that cause hair growth?

9 citations , July 2014 in “Experimental Dermatology”

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Development of Finasteride/PHBV@Polyvinyl Alcohol/Chitosan Reservoir-Type Microspheres as a Potential Embolic Agent: From In Vitro Evaluation to Animal Study

research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro evaluation to animal study

14 citations , January 2020 in “Biomaterials Science”

Created microspheres show potential for safe and effective use in prostate artery embolization.

research 5-alpha-reductase inhibitors for lower urinary tract symptoms secondary to benign prostatic obstruction

1 citations , November 2015 in “Cochrane library”

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase

research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase

5 citations , February 1997 in “Bioorganic & Medicinal Chemistry”

New compounds were made that effectively block a specific enzyme related to androgen conditions.

research Molecular interactions of progesterone derivatives with 5α-reductase types 1 and 2 and androgen receptors

19 citations , March 2010 in “Steroids”

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

research Novel type 1 5a-reductase Inhibitors with Antiproliferative Potential on LNCaP cells

June 2023 in “Oriental Journal of Chemistry/Oriental journal of chemistry”

New compounds may help treat prostate cancer by reducing cell growth.

research Trimodal mini-invasive therapy for stable-phase Peyronie's disease: a two-center real-life prospective pilot study

September 2025

PRP injections with tadalafil and stretching safely improved Peyronie's symptoms but didn't significantly change curvature long-term.

research Dipyridamole-Associated Shock and Pulmonary Edema; Oxcarbazepine-Induced Resistant Ventricular Fibrillation; Finasteride-Induced Pseudoporphyria; Suicidal Ideation Associated with Asenapine; Rediscovering Adverse Anticholinergic Effects; Prevalence of Adverse Drug Events in Ambulatory Care

1 citations , October 2011 in “Hospital Pharmacy”

Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment

research Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment

December 2023 in “Journal of Medicinal Chemistry”

A new topical treatment for hair loss shows strong hair growth effects with low toxicity.

research Referee report. For: Recent advances in treatment for Benign Prostatic Hyperplasia [version 1; referees: 2 approved]

January 2015 in “Faculty of 1000 Research Ltd”

BPH treatment improved with personalized medicine, new drugs, and less invasive surgeries.

Activation of Platelet-Rich Plasma by Pulse Electric Fields: Voltage, Pulse Width, and Calcium Concentration Can Be Used to Control and Tune the Release of Growth Factors, Serotonin, and Hemoglobin

research Activation of platelet-rich plasma by pulse electric fields: Voltage, pulse width and calcium concentration can be used to control and tune the release of growth factors, serotonin and hemoglobin

3 citations , April 2021 in “PLoS ONE”

Pulse electric fields can control the release of growth factors and serotonin from platelet-rich plasma, offering a tailored approach to wound healing.

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