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Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.

Pachyonychia congenita is linked to a keratin gene on chromosome 17.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

Upadacitinib effectively treats pyoderma gangrenosum.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

A new microneedle patch significantly improves melanoma treatment by using a special material to activate cancer-fighting drugs and disrupt cancer cells.

The gene URB is more active in human hair growth cells and responds to a hair-related hormone.

Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.

PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.

5ARIs like finasteride can help prevent prostate cancer and treat BPH, but guidelines should be updated to reflect this.

Increased K+ permeability alone may not promote hair growth.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

A new type of nerve cell involved in itch perception was discovered.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Finasteride and dutasteride's effects are mainly due to target binding saturation and slow enzyme turnover.

Activating TRPV3 stops human hair growth.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

A 5-year-old girl with a rare skin disorder was effectively treated with skin creams instead of oral medication.

The prolactin gene polymorphism doesn't affect cashmere quality in these goats.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

Certain peptides can prevent hair loss in young rats caused by a cancer drug.

Quick, selective detection of tadalafil and finasteride in human plasma developed.

A patient developed a blister at the injection site after hepatitis C treatment.

PM-9, like finasteride, may help treat certain diseases by blocking a key enzyme.

Ozone and procaine boost the release of healing factors in platelet-rich plasma.