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Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

CXCR2 in skin cells promotes tumor growth.

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

P2X₃-IR fibers are widespread in rat skin and likely help detect pain.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

p63 is essential for controlling epithelial stem cells and tissue health.

PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.

Rats can develop an immune response to prion protein peptides, but it may cause severe skin issues in older rats.

The patient had paraneoplastic pemphigus without mucosal involvement.

Newborns with the common rash Erythema Toxicum have many active mast cells in their skin, but these cells don't produce the LL-37 peptide.

A severe form of Netherton syndrome caused by a specific gene mutation led to neonatal deaths in a family.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

HPDAlR nanoparticles greatly improve skin wound healing without toxicity.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

NLRP1 helps melanoma tumors grow by boosting inflammasome activation and reducing caspase-3 activity.

BTNL2 helps protect hair follicles from immune attacks.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The protein called small nuclear ribonucleoprotein polypeptide E is identified as a cause of a type of hair loss without other symptoms.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

The most common sign of aging at the gene level is more Ectodysplasin A2 Receptor (EDA2R) being made.

Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

CGRP-IR axons may help maintain and renew tissues.

TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.