138 citations
,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
92 citations
,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
71 citations
,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
68 citations
,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
51 citations
,
August 2013 in “Journal of Investigative Dermatology” Human skin cells can create new hair follicles when transplanted into mice.
47 citations
,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
46 citations
,
January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
46 citations
,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
45 citations
,
December 2018 in “Lasers in Medical Science” LLLT promotes hair growth and improves hair density safely in men and women.
44 citations
,
June 2009 in “Biomaterials” Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.
41 citations
,
March 1998 in “Archives of Dermatological Research” The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
32 citations
,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
31 citations
,
August 2019 in “Regenerative Medicine” Human placenta hydrogel helps restore cells needed for hair growth.
31 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
31 citations
,
April 1999 in “Dermatologic Clinics” Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
31 citations
,
October 2012 in “Archives of ophthalmology” Laser hair reduction near the eyebrows can cause serious eye injuries even with safety measures.
28 citations
,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
28 citations
,
October 2011 in “International Journal of Molecular Medicine” Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
26 citations
,
February 2012 in “Journal of Investigative Dermatology” Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.
24 citations
,
February 2015 in “Experimental Cell Research” NFIC helps human dental stem cells grow and become tooth-like cells.
24 citations
,
January 2015 in “Annals of Dermatology” Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
24 citations
,
March 2001 in “Journal of Endocrinology/Journal of endocrinology” Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
20 citations
,
July 2020 in “Expert Opinion on Biological Therapy” Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
20 citations
,
October 2008 in “Archives of dermatological research” Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
18 citations
,
July 2014 in “Molecular Medicine Reports” UVB radiation changes the levels of certain microRNAs in skin cells, which may affect cell survival and hair growth.
17 citations
,
June 2019 in “BMC genomics” Non-coding RNAs help control hair growth in cashmere goats.
17 citations
,
December 2015 in “BMC Complementary and Alternative Medicine” A new plant extract from Avicennia marina could potentially be used to treat common hair loss.
16 citations
,
April 2015 in “Lasers in Surgery and Medicine” Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
13 citations
,
August 2020 in “Frontiers in Cell and Developmental Biology” Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.
13 citations
,
October 2017 in “Bioscience, Biotechnology, and Biochemistry” Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.