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GlossaryPapules

small, raised, solid skin bumps under 1 centimeter

Papules are small, raised, solid bumps on the skin that are usually less than 1 centimeter in diameter. They can be a sign of various conditions, including acne, dermatitis, or psoriasis, and are often inflamed but do not contain pus.

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research Clinical and Molecular Diagnostic Criteria of Congenital Atrichia with Papular Lesions11This paper originally appeared in issue 117:1662–1665, 2001. Following publication the authors indicated that important corrections at page proof were not taken in. To ensure that the paper is published as intended, the editors have decided to reproduce the contents in full.

69 citations , May 2002 in “Journal of Investigative Dermatology”

Congenital atrichia with papular lesions is often misdiagnosed, and new diagnostic criteria can improve accuracy.

research Congenital atrichia with papular lesions

8 citations , January 2014 in “Indian Journal of Paediatric Dermatology”

Congenital atrichia with papular lesions causes permanent hair loss and skin bumps from birth.

research Papular Acantholytic Dyskeratosis of the Vulva: A Case Report and Literature Review

4 citations , January 2025 in “Clinical Cosmetic and Investigational Dermatology”

Papular acantholytic dyskeratosis of the vulva is a rare, benign skin condition that can be managed conservatively.

research A papular eruption on the face. A distinct subtype of lichen planopilaris?

1 citations , March 2013 in “Journal of Dermatological Case Reports”

A rare skin condition affected only the facial hair of a 46-year-old man.

research Bilateral madarosis due to papular mucinosis

1 citations , January 2014 in “Indian journal of dermatology, venereology, and leprology”

Papular mucinosis can cause eyebrow hair loss, but treatment can lead to regrowth.

research A linear and reticulate crusted keratotic papulopustular eruption: a rare presentation of PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) complex

August 2024 in “Postgraduate Medical Journal”

A rare skin reaction from cancer treatment was successfully managed with topical treatments and antihistamines.

research Mucinous Lupus Alopecia with Papulonodular Mucinosis as a Sole Cutaneous Manifestation of Systemic Lupus Erythematosus

November 2023 in “International Journal of Trichology”

A rare form of lupus caused hair loss and skin bumps, diagnosed through biopsy, improved partially with treatment.

Papular Atrichia: A Case Report of an 8-Year-Old Girl

research Papular atrichia

April 2020 in “International journal of research in dermatology”

An 8-year-old girl has a rare, irreversible hair loss condition caused by a genetic mutation.

PRIDE Complex: Papulopustules, Paronychia, Hair Growth Abnormalities, Itching, and Dryness Due to EGFR Inhibitors

research PRIDE Complex (Papulopustules and/or Paronychia, Regulatory Abnormalities of Hair Growth, Itching, Dryness Due to EGFR Inhibitors)

August 2025 in “JEADV Clinical Practice”

PRIDE complex side effects from EGFR inhibitors can be managed without stopping treatment.

research Atrichia congenita with papular lesions: A rare cause of pediatric alopecia

July 2025 in “TURKDERM”

This rare genetic disorder causes permanent hair loss and skin bumps from birth.

research Diffuse loss of hair with papules

September 2024 in “Cosmoderma”

The young man has complete hair loss and skin bumps, with no other health issues or family history.

research Cutaneous sarcoidosis masquerading as papular amyloidosis revealed post--hair removal

January 2023 in “Indian dermatology online journal”

Skin problems after waxing led to a sarcoidosis diagnosis.

research A rare cause of irrevocable childhood alopecia feigning alopecia universalis: Atrichia congenita with papular lesions

September 2022 in “IP Indian journal of clinical and experimental dermatology”

An 8-year-old girl has a rare genetic disorder causing complete, irreversible hair loss and skin bumps.

research The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) syndrome

90 citations , August 2006 in “British Journal of Dermatology”

PRIDE syndrome includes skin and hair issues from cancer treatment with EGFR inhibitors.

research A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions

47 citations , April 2000 in “Experimental Dermatology”

A new gene mutation causes a rare type of hair loss.

research Atrichia and Papular Lesions: Report of a Case

18 citations , January 1992 in “Dermatology”

A 4-year-old girl has a rare condition causing hairlessness and skin bumps, but normal teeth and sweating.

research Variant 1859G→A (Arg620Gln) of the “Hairless” Gene: Absence of Association with Papular Atrichia or Androgenetic Alopecia

14 citations , July 2001 in “American Journal of Human Genetics”

Haplogroup X found in Altaian population supports Amerindian origin.

research Congenital atrichia with papular lesions resulting from novel mutations in human hairless gene in four consanguineous families

11 citations , February 2011 in “The Journal of Dermatology”

Mutations in the hairless gene cause a rare form of permanent hair loss.

research Tacrolimus ointment: summarizing two decades of experience in off-label use. Use in rosacea, seborrheic dermatitis, papulosquamous dermatoses, lupus erythematosus, eczematous dermatoses, alopecia, and other diseases

January 2026 in “Vestnik dermatologii i venerologii”

Tacrolimus ointment is effective for various skin conditions but needs more research for long-term effects.

Trichoscopy as a Method of Differential Diagnosis of Non-Scarring Hair Loss and Papulo-Squamous Disorders of the Scalp

research Trichoscopy as a method of differential diagnostic of non-scarring hair loss and papulo-squamous disorders of the scalp

December 2019 in “Дерматологія та венерологія”

Trichoscopy is a useful tool for diagnosing hair and scalp disorders.

Fibrous Papule of the Face, Similar to Tuberous Sclerosis Complex-Associated Angiofibroma, Shows Activation of the Mammalian Target of Rapamycin Pathway: Evidence for a Novel Therapeutic Strategy?

research Fibrous Papule of the Face, Similar to Tuberous Sclerosis Complex-Associated Angiofibroma, Shows Activation of the Mammalian Target of Rapamycin Pathway: Evidence for a Novel Therapeutic Strategy?

12 citations , February 2014 in “PLoS ONE”

Topical rapamycin may effectively treat fibrous papules on the face.

research Atrichia with papular lesions

8 citations , January 2011 in “International journal of trichology”

Accurate diagnosis of APL is crucial to avoid unnecessary treatments.

research Therapeutic response of facial papules and inflammation in frontal fibrosing alopecia to low-dose oral isotretinoin

7 citations , April 2020

Low-dose oral isotretinoin improved hair loss and facial bumps in patients with a specific type of hair loss.

Acral Lymphomatoid Papulosis in a 31-Year-Old Woman

research Frontal fibrosing alopecia presenting with rapidly spreading facial papules in a premenopausal woman: Case report and review

1 citations , August 2018 in “Journal of the American Academy of Dermatology”

A young woman developed facial bumps before hair loss, which is unusual for her condition.

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Related Terms

Research

research Congenital atrichia with papular lesions

research Papular Acantholytic Dyskeratosis of the Vulva: A Case Report and Literature Review

research A papular eruption on the face. A distinct subtype of lichen planopilaris?

research Bilateral madarosis due to papular mucinosis

research A linear and reticulate crusted keratotic papulopustular eruption: a rare presentation of PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) complex

research Mucinous Lupus Alopecia with Papulonodular Mucinosis as a Sole Cutaneous Manifestation of Systemic Lupus Erythematosus

research Papular atrichia

research PRIDE Complex (Papulopustules and/or Paronychia, Regulatory Abnormalities of Hair Growth, Itching, Dryness Due to EGFR Inhibitors)

research Atrichia congenita with papular lesions: A rare cause of pediatric alopecia

research Diffuse loss of hair with papules

research Cutaneous sarcoidosis masquerading as papular amyloidosis revealed post--hair removal

research A rare cause of irrevocable childhood alopecia feigning alopecia universalis: Atrichia congenita with papular lesions

research The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) syndrome

research A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions

research Atrichia and Papular Lesions: Report of a Case

research Variant 1859G→A (Arg620Gln) of the “Hairless” Gene: Absence of Association with Papular Atrichia or Androgenetic Alopecia

research Congenital atrichia with papular lesions resulting from novel mutations in human hairless gene in four consanguineous families

research Tacrolimus ointment: summarizing two decades of experience in off-label use. Use in rosacea, seborrheic dermatitis, papulosquamous dermatoses, lupus erythematosus, eczematous dermatoses, alopecia, and other diseases

research Trichoscopy as a method of differential diagnostic of non-scarring hair loss and papulo-squamous disorders of the scalp

research Fibrous Papule of the Face, Similar to Tuberous Sclerosis Complex-Associated Angiofibroma, Shows Activation of the Mammalian Target of Rapamycin Pathway: Evidence for a Novel Therapeutic Strategy?

research Atrichia with papular lesions

research Therapeutic response of facial papules and inflammation in frontal fibrosing alopecia to low-dose oral isotretinoin

research Acral lymphomatoid papulosis

research Persistent Papular Plaques on the Face

research Congenital atrichia with papular lesions

research Atrichia with papular lesions in a Taiwanese patient without hairless (HR) gene mutation

research The ginseng pimple: an inflammatory papule following ginseng consumption

research Solitary papule with central crater in a young man: Dermoscopy picks the clue

research Frontal fibrosing alopecia presenting with rapidly spreading facial papules in a premenopausal woman: Case report and review