research Mechanism of action to accelerate second deep degree scald wound healing by endogenous EGF
Endogenous EGF helps heal second-degree scald wounds faster.
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research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration
Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
research Multipotent adult progenitor cells grown under xenobiotic-free conditions support vascularization during wound healing
Xenobiotic-free progenitor cells improve wound healing and blood vessel formation.
research Melatonin membrane receptors in peripheral tissues: Distribution and functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Application of mesenchymal stem cells for anti-senescence and clinical challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research The topography of fibrous scaffolds modulates the paracrine function of Ad-MSCs in the regeneration of skin tissues
The shape of fibrous scaffolds can improve how stem cells help heal skin.
research Applications of Mesenchymal Stem Cells in Anti-Aging and Skin Regeneration
Mesenchymal stem cells can help delay skin aging and improve wound healing.
research The Hair Follicle: A Paradoxical Androgen Target Organ
Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
research Up-to-date Clinical Trials of Hair Regeneration Using Conditioned Media of Adipose-Derived Stem Cells in Male and Female Pattern Hair Loss
Adipose-derived stem cells (fat cells) show promise in treating hair loss in both men and women.
research Wound-healing effects of frozen-thawed allogeneic fibroblast sheet transplantation and xenogeneic fibroblast cell sheet transplantation cultured on a new substrate
Frozen-thawed fibroblast sheets enhance wound healing and hair growth in mice.
research The roles of hepatocyte growth factor family members in androgen-regulation of human hair growth. A comparison of the expression of hepatocyte growth factor family members, HGF and MSP, and their receptors, c-Met and RON, in isolated hair follicles from normal and androgenetic alopecia (balding) scalp.
Balding hair follicles have reduced growth factors and increased inhibitory factors, suggesting new treatment paths for hair loss.
research Microskin‐Inspired Injectable MSC‐Laden Hydrogels for Scarless Wound Healing with Hair Follicles
MSC-laden hydrogels enable scarless wound healing with hair growth.
research Utilizing the hair follicle to dissect the regulation and autocrine/paracrine activities of prolactin in humans
Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.
research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research Modulation of glucocorticoid action and the treatment of type-2 diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
research Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition
Piperonylic acid speeds up wound healing by reducing inflammation and boosting collagen.
research Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction
Special fiber materials boost the healing properties of certain stem cells.
research Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle
A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
research 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance
DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
research MECHANISM OF ACTION OF AVICENNIA MARINA HEARTWOOD EXTRACT AND AVICEQUINONE C ON HUMAN DERMAL PAPILLA CELLS ISOLATED FROM ANDROGENIC ALOPECIA PATIENTS
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
research Action Mechanism of Chamaecyparis obtusa Oil on Hair Growth
Chamaecyparis obtusa oil may help hair grow similarly to minoxidil by affecting certain growth markers and cell factors.
research Hair growth promoting effect and action mechanism of Chrysanthemum zawadskii extract
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
research Modelling androgen synthesis and action during human sexual differentiation
Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
research Melatonin induces a stimulatory action on the scrotal skin components of Soay ram in the non-breeding season
Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research Gonadal Sex Steroids: Production, Action and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research The senescence-like activity of BMS-470539 is associated with anti-fibrotic actions in models of dermal fibrosis
BMS-470539 reduces skin fibrosis and inflammation.