research NEW GENERATION OF VACCINE TECHNOLOGIES
New vaccine technologies are improving global health by making vaccines more effective and long-lasting.
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research Sustained release of dermal papilla-derived extracellular vesicles from injectable microgel promotes hair growth
Injecting a special gel with human protein particles can help hair grow.
research Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications
Adrenal disorders can cause lasting brain and behavior issues in children.
research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
research Immunosenescence and inflammaging in Parkinson’s disease: mechanisms and therapeutic prospects
Age-related immune changes worsen Parkinson's disease, suggesting new treatment strategies.
research ADVANCES IN FUNCTIONAL NEUROSURGERY – MACHINE LEARNING, NEURAL ENGINEERING AND ROBOTICS IN TREATMENT OF NEURODEGENERATIVE DISORDERS
AI and robotics are improving treatment and monitoring of neurodegenerative disorders like Parkinson's.
research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and balance through specific signaling.
research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
Hormones and genes affect hair growth and male baldness.
research Effects of all-trans retinoic acid on goat dermal papilla cells cultured in vitro
All-trans retinoic acid at high doses harms goat hair growth cells and could be bad for hair growth.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research Microtechnology-based methods for organoid models
Microtechnology methods improve organoid production for medical research.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer
Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
research Platelet‐rich plasma and regenerative dentistry
Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.
research SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells
SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
research Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research TGFβ and cancer metastasis: an inflammation link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research 5α-Reduced glucocorticoids: a story of natural selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-like Growth Factor 1
IGF-1 increases whisker growth in transgenic mice.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications
Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
research Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages
The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Alopecia and ocular alterations: a role for Minoxidil?
Minoxidil, a common alopecia medication, might cause eye changes due to its properties and lack of tissue selectivity.
research Regeneration, Wound Healing and Cancer
The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
research The multifaceted regulatory effect of icariin on macrophages: a mini-review
Icariin can regulate macrophages and may help treat inflammation, cancer, bone disorders, and fibrotic diseases.
research EXPLORING THE ROLE OF UMBILICAL CORD AND CORD BLOOD IN REGENERATIVE MEDICINE
Umbilical cord and cord blood stem cells are promising for treating chronic diseases due to their versatility and ethical acceptability.
research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.