research SOX9 in organogenesis: shared and unique transcriptional functions
SOX9 is essential for the development of various organs and hair follicles.
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840-870 / 1000+ results research STAT3 Partly Inhibits Cell Proliferation via Direct Negative Regulation of FST Gene Expression
The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
research The Role of the Gut Microbiome and Microbial Dysbiosis in Common Skin Diseases
Gut health affects skin diseases, and probiotics might help.
research New insights into the phenomenon of remissions and relapses in autoimmune diseases and the puzzle of benign autoantibodies in healthy individuals
Autoimmune diseases with high tissue recovery often relapse and remit, while those with low recovery rarely remit.
research Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep
Editing the FGF5 gene in sheep increases fine wool growth.
research In Vitro and In Vivo Assessment of Metabolic Drug Interaction Potential of Dutasteride with Ketoconazole
Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.
research Clinical, Hormonal, Behavioral, and Genetic Characteristics of Androgen Insensitivity Syndrome in a Brazilian Cohort: Five Novel Mutations in the Androgen Receptor Gene
Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Allosteric interactions prime androgen receptor dimerization and activation
Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.
research SAT-288 Successful Virilization of a PAIS Patient with a Missense Mutation In The Ligand-binding Domain Of The Androgen Receptor with Combined High-dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha
Minoxidil might partially activate estrogen receptors, affecting hair growth.
research Nonsteroidal Selective Androgen Receptors Modulators (SARMs): Designer Androgens with Flexible Structures Provide Clinical Promise
SARMs may offer benefits by boosting muscle effects without unwanted side effects.
research Androgen action on human skin – from basic research to clinical significance
Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
research Different phenotypes in a family with androgen insensitivity caused by the same M780I point mutation in the androgen receptor gene.
The same gene mutation can cause different symptoms in family members.
research 5α-reduction of epitestosterone is catalysed by human SRD5A1 and SRD5A2 and increases androgen receptor transactivation
5α-reductases increase epitestosterone's effect on androgen receptors.
research Androgen regulation of a specific gene in hamster flank organs
Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
research Female androgenetic alopecia with male pattern caused by an androgen-producing tumor
Androgen-producing ovarian tumors can cause male-pattern hair loss in women.
research 5α-reductase Inhibitors: Finasteride and Dutasteride in Feminising Therapy
Finasteride and dutasteride have limited use in feminising therapy and are not recommended for routine use.
research Diseases of the Canine Prostate Gland
The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.
research 5α-reductase Inhibitors: Finasteride and Dutasteride in Feminising Therapy
Finasteride and dutasteride are not recommended for feminizing therapy due to limited effectiveness and potential risks.
research Familial Cortisol Resistance: Differential Diagnostic and Therapeutic Aspects
The woman had a genetic condition causing high cortisol and androgen levels, treatable with dexamethasone.
research An Open Randomized Comparative Study of an Oral Contraceptive Containing Ethinyl Estradiol and Cyproterone Acetate with and without the GnRH Analogue Goserelin in the Long-Term Treatment of Hirsutism
The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
research 0980 Tanshinone capsule enhances hair follicle regeneration in a mouse model of androgenetic alopecia via IGF1 and Wnt/β-catenin pathway
Tanshinone Capsule may help regrow hair by boosting specific cell signals.
research Platelet-rich plasma therapy in the treatment of androgenic alopecia – review
Platelet-rich plasma therapy shows promise in treating hair loss caused by androgenic alopecia.
research Referee report. For: Hair greying in castrated mice [version 1; peer review: 1 approved with reservations]
Androgen loss may speed up hair greying.
research Male Androgenetic Alopecia - A Review of Current Treatments
Current treatments can slow hair loss and promote regrowth, with hair transplantation being most effective for advanced cases.
research Male Androgenetic Alopecia - A Review of Current Treatments
Current treatments can slow hair loss and promote regrowth, with hair transplantation being most effective for advanced cases.
research Development and validation of a comprehensive in vitro organ model for androgenetic alopecia
The new model mimics hair loss and helps test treatments.
research Alopécie frontale fibrosante : à propos de trois cas pédiatriques
Frontal fibrosing alopecia can occur in children, not just postmenopausal women.
research Advances in Hair Transplantation: Longitudinal Partial Follicular Unit Transplantation
New hair transplant method allows for hair regrowth in the donor area and less scarring.