research Genetic and molecular aspects of androgenetic alopecia
Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.
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270-300 / 1000+ resultsresearch Palmoplantar pustulosis–like eruption following tofacitinib therapy for juvenile idiopathic arthritis
Tofacitinib can cause skin eruptions similar to palmoplantar pustulosis.
research Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris
The study created a mouse model that survives longer and shows fewer symptoms of pemphigus vulgaris.
research Janus kinase inhibition for the treatment of refractory frontal fibrosing alopecia: A case series and review of the literature
JAK inhibitors, like ruxolitinib, may effectively treat frontal fibrosing alopecia.
research The Important Role of Leptin in Modulating the Risk of Dermatological Diseases
Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
research IMMUNOPATHOLOGY OF THE HUMAN HAIR FOLLICLE
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research TRPV Channels in Osteoarthritis: A Comprehensive Review
TRPV channels are important in osteoarthritis and could be key to new treatments.
research The heme-responsive PrrH sRNA regulates Pseudomonas aeruginosa pyochelin gene expression
PrrH sRNA controls pyochelin production in *Pseudomonas aeruginosa*.
research Nivolumab-Induced Alopecia Areata: A Case Report and Literature Review
Nivolumab can cause hair loss as a rare side effect.
research 649 Gut microbiota plays a role in the development of alopecia areata
The gut microbiome affects the development of alopecia areata.
research Comprehensive treatment of Cronkhite-Canada syndrome: A case report and literature review
Traditional Chinese medicine may help relieve symptoms of Cronkhite-Canada syndrome.
research Adalimumab-induced psoriatic alopecia/alopecia areata-like reaction in a patient with Crohn's disease
A patient with Crohn's disease grew back their hair after stopping Adalimumab, which had caused hair loss.
research Onset of frontal fibrosing alopecia during inhibition of Th1/17 Pathways with ustekinumab
Ustekinumab treatment didn't prevent frontal fibrosing alopecia.
research No evidence for follicular keratinocyte hyperproliferation in acne lesions as compared to autologous healthy hair follicles
Acne lesions don't show increased keratinocyte growth compared to healthy hair follicles.
research T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases
EDA signaling is linked to skin disorders, various cancers, and liver disease.
research Differential expression of mTOR signaling pathway proteins in lichen planopilaris and frontal fibrosing alopecia
The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.
research Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Advances in genetic and molecular understanding of Omenn syndrome - implications for the future
Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
research The immunopathobiology of lichen planopilaris
Immune system failure in hair follicles causes lichen planopilaris, leading to hair loss.
research Role of Metformin in Polycystic Ovary Syndrome (PCOS): Related Infertility
Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
research Alopecia: from clinic to preclinic and back
Many people suffer from hair loss, which is caused by a disruption in hair growth, and there is a need for personalized treatments and new drugs.
research Comprehensive single-cell transcriptomic profiling of the scalp from patients with moderate-to-severe alopecia areata
Alopecia areata involves immune system issues and specific cell types that disrupt hair growth, leading to hair loss.
research Metabolic and Vascular Inflammation in Alopecia Areata: Linking Uric Acid, Lipid Imbalance and ICAM ‐1 Upregulation
Improving blood vessel health and controlling uric acid may help manage alopecia areata.
research 0040 Machine learning algorithms as tools for identifying predictive autoantibody biomarkers in pemphigus vulgaris
Machine learning can help identify biomarkers for personalized Pemphigus vulgaris treatment.
research Role of UVA-driven cellular senescence via mTOR activation in dihydrotestosterone-induced hair loss in androgenetic alopecia mouse model
UVA exposure worsens hair loss by activating a specific cell pathway.
research Complete defect in PA-PLA1α secretion function leading to autosomal recessive woolly hair and hypotrichosis: insights from a novel compound heterozygous LIPH variant study in a Chinese pedigree
A new genetic variant in the LIPH gene causes hair growth issues in a Chinese patient.
research A brief report on PCOS: and its inducing model
PCOS causes hormonal imbalance, leading to symptoms like irregular periods and infertility.
research Homocysteine in androgenetic alopecia: A case control study and observational experiments on mice
Higher homocysteine levels may inhibit hair growth and are linked to androgenetic alopecia.
research Serum Clusterin Level in with Post Adolescent Acne
Serum clusterin may play a key role in the inflammation and immune response in post-adolescent acne.