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SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

Cats with abnormal hair had DSG4 gene changes causing hair problems.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.

A new genetic variant causes BRESHECK syndrome by disrupting cell growth and stress response.

PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.

A new gene mutation causes a rare type of hair loss.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Patched1 helps prevent tumors by controlling cell growth.

Improved genetic diagnosis of PCOS can lead to better patient outcomes.

TBX3 gene affects pigmentation and marking formation in Dun Mongolian horses.

ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.

Scientists created cell lines to study a genetic skin disorder using CRISPR technology.

Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.

Gene expression, especially Dkk4, is key to cat color patterns.

The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

A gene mutation in Lama3 is linked to a common type of hair loss.

LncRNA RP11-818024.3 helps hair growth and recovery in hair loss by boosting cell survival and reducing cell death.

A new therapy for a skin blistering condition has not been developed yet.

The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.

Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.

Lymphotoxin-β is crucial for proper skin development in embryos.

Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.

Pimozide treatment resolved cysts and partially restored cheek fat in a man with Barraquer–Simons syndrome.

Keratin 17 gene mutations cause both steatocystoma multiplex and pachyonychia congenita type 2.

Key genes and pathways improve wool quality in Zhexi Angora rabbits.