research Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing
CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.
Search
for
Sort by
Research
870-900 / 1000+ results 
research Update on Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) affects 6%-15% of women of reproductive age, causing symptoms like acne and hair loss, and increasing the risk of type 2 diabetes and heart disease; it's managed through diet, exercise, and medications like Metformin and hormonal contraceptives.
research Polycystic ovary syndrome in North America
PCOS is a common and costly condition in North American women, causing various health issues like obesity, diabetes, and fertility problems.
research Polycystic ovary syndrome: A review for dermatologists
A team approach is crucial for managing PCOS, with dermatologists playing a key role.
research Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery
research Gynecological and dermatological aspects of diagnostics of polycystic ovary syndrome from puberty to menopause
PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.
research Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene
The wavy coat in NCT mice is caused by multiple genes, including a mutation in the Prss53 gene.
research ISID1343 - Efficacy of asymmetric siRNA targeting androgen receptor for the treatment of androgenetic alopecia
The conclusion is that a treatment called cp-asiAR can reduce hair loss and promote hair growth, making it a potential new therapy for androgenetic alopecia.
research 269 Down-regulatory role of cholecystokinin on psoriatic epidermal inflammation
Cholecystokinin may help reduce skin inflammation in psoriasis.
research Cyberspace Chat: Safe management of patients on Plavix® (clopidogrel) for hair restoration surgery (HRS)
Doctors should collaborate with the patient's primary care physician to decide if it's safe to stop taking Plavix before hair restoration surgery, considering the risk and benefit.
research The pressing need for standardization in epidemiologic studies of PCOS across the globe
The article concludes that global standardization in PCOS research is crucial for accurate diagnosis and understanding of the condition.
research Contraceptive implants considered 'safe'
Some birth control pills increase blood clot risk; use them for specific conditions only.
research Transcriptome-based Selection and Validation of Optimal House-keeping Genes for Skin Research in Goats (Capra hircus)
NCBP3, SDHA, and PTPRA are the best genes for normalizing goat skin experiments.
research Evaluation Asprosin Level in Polycystic Ovary Syndrome and Its Association with Fetuin a and Some Biochemical Parameter
Fetuin A levels are higher in PCOS patients, while asprosin levels show no difference.
research Genosomes: An introspection into transfection, future perspectives and applications
Genosomes are promising for safe and effective gene delivery in therapy.
research Clinical Efficacy and Cholesterol-Lowering Effects of Inclisiran
Inclisiran is effective at lowering cholesterol.
research A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation
A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
research Homoeopathic management of polycystic ovarian syndrome – A case series
Homeopathic treatment improved symptoms of PCOS in seven patients.
research A Global Survey of Ethnic Indian Women Living with Polycystic Ovary Syndrome: Concerns, Diagnosis Experiences, Quality of Life, and Use of Treatment Methods
Ethnic Indian women with PCOS face significant care gaps, needing better support and information.
research Cost-effectively dissecting the genetic architecture of complex wool traits in rabbits by low-coverage sequencing
Low-coverage sequencing is a cost-effective way to identify genes related to wool traits in rabbits.
research High-performance liquid chromatographic determination of finasteride in human plasma using direct injection with column switching
New method detects finasteride in plasma quickly and accurately without clean-up.
research Changes in the serum metabolomics of polycystic ovary syndrome before and after compound oral contraceptive treatment
COC treatment improves hormone and metabolic levels in PCOS patients.
research Altered autonomic neural control of the cardiovascular system in patients with polycystic ovary syndrome
People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.
research Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies
CRISPR/Cas9 has improved precision and control but still faces clinical challenges.
research Parameters of obesity in polycystic ovary syndrome
Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.
research ASSESSMENT OF HEALTH RELATED QUALITY OF LIFE IN POLY CYSTIC OVARIAN SYNDROME PATIENTS AND FACTORS AFFECTING OVARIAN FOLLICULAR SIZE
PCOS affects quality of life most in infertility, and treatments vary by weight.
research Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality
Extracellular vesicles could help tailor drug treatments, but more research is needed.
research Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hair
The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.
research Construction and Verification of Recombinant Follicle-specific Expression Vector
The vector successfully directed specific gene expression in hair follicles.
research K ATP Channels and Cardiovascular Disease
K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.