47 citations
,
November 1982 in “Journal of Cardiovascular Pharmacology” Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
10 citations
,
November 2017 in “Letters in drug design & discovery” Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.
79 citations
,
October 2003 in “PubMed” Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
June 2012 in “Nature digest” A substance called prostaglandin D2 is linked to stopping hair growth in men with common baldness.
8 citations
,
April 2004 in “The Journal of Urology” Doxazosin and finasteride negatively affect sexual function in men with BPH.
74 citations
,
September 2003 in “The Journal of Immunology” Activating PKCα in skin causes cell death and inflammation through different pathways.
3 citations
,
September 1980 in “Experientia” Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
1 citations
,
December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
16 citations
,
December 2016 in “Molecular Medicine Reports” Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.
April 2007 in “The Journal of Urology” Finasteride reduces bleeding risk during prostate surgery.
July 2026 in “Journal of Investigative Dermatology” 9 citations
,
June 2021 in “Journal of Inflammation Research” Euph E and Euri A from Euphorbia neriifolia help control inflammation and immune response in cells.
32 citations
,
July 2003 in “Histochemistry and Cell Biology” 8 citations
,
June 2024 in “Pharmaceutics” PEA-ENL improves skin delivery and reduces inflammation without side effects.
April 2023 in “Journal of Investigative Dermatology” Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
1 citations
,
January 1989 in “Carcinogenesis” Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
14 citations
,
June 2015 in “Toxicology and Industrial Health” Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
5 citations
,
January 2021 in “IEEE Access” Electric pulses can effectively activate platelets and release growth factors, offering a better alternative to traditional methods.
12 citations
,
November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
1 citations
,
December 2012 in “I P Pavlov Russian Medical Biological Herald” Finasteride increases P-glycoprotein activity in the liver and kidney.
July 2026 in “Pharmaceuticals” Plant-derived extracellular vesicles show promise for delivering drugs and treating diseases.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
February 2023 in “riUfes (Universidade Federal do Espírito Santo)” High testosterone affects blood vessel function, with estrogen playing a key role in maintaining heart health.
June 2026 in “Oriental Journal Of Chemistry” Steroid 12 shows promise as a targeted treatment for prostate cancer by selectively reducing cell growth and increasing cell death.
3 citations
,
February 2019 in “Molecular genetics and metabolism” The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.
MIR135b affects wound healing by targeting genes, and PDRN may help heal wounds by altering this pathway.
January 2026 in “Applied Sciences” Cyclic ADP-ribose helps regulate calcium and signals that promote hair growth in hair follicle cells.
October 2021 in “Journal of Investigative Dermatology” Dkk4 protein is necessary for the proper development and arrangement of hair follicles.
December 2021 in “Figshare” The study investigated the role of Bardet-Biedl syndrome 7 (BBS7) in maintaining periodontal ligament (PDL) homeostasis under occlusal hypofunction conditions. RNA sequencing of 34 human teeth revealed that BBS7 expression was downregulated in hypofunctional PDL, leading to atrophic changes such as reduced PDL cell numbers, altered collagen fiber alignment, and decreased blood vessel diameter. The study found that Sonic hedgehog (Shh) signaling activity was closely linked to BBS7 expression, and BBS7 knockdown suppressed cell migration and angiogenesis in vitro. These findings suggested that BBS7 is crucial for maintaining Shh signaling activity and PDL homeostasis.