These medications for BPH have known risks and may have new side effects.
These medications for BPH have known risks and may have new side effects.
March 2026 in “The Aging Male” PDE5 inhibitors cause earlier adverse events in BPH treatment, requiring careful monitoring.
15 citations
,
July 2016 in “Urologic Clinics of North America” Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
April 2018 in “The Journal of Urology” Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.
Tadalafil may reduce the risk of major heart events and blood clots in men with urinary symptoms.
26 citations
,
December 2023 in “Prostate International” Medications for BPH can have significant side effects, so understanding these risks is important for treatment decisions.
9 citations
,
December 2020 in “Dermatologic Therapy” Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men increases the risk of sexual dysfunction.
April 2022 in “The Journal of Sexual Medicine” Finasteride alone increases suicide risk, but combining it with other treatments reduces this risk.
35 citations
,
May 2020 in “Frontiers in Pharmacology” Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
4 citations
,
June 2023 in “Frontiers in Aging” Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
June 2026 in “World Journal of Urology” Long-term finasteride use may lead to earlier use of ED medication and lower prostate cancer diagnosis rates.
April 2026 in “The Journal of Urology” Low-dose finasteride may increase erectile dysfunction risk over time.
October 2013 in “Urology Times eNews” The FDA approved using Cialis with Proscar for better treatment options.
April 2012 in “The Journal of Urology” Persistent ED in Propecia users is not due to abnormal blood flow.
PRP injections with tadalafil and stretching safely improved Peyronie's symptoms but didn't significantly change curvature long-term.
June 2018 in “The Journal of Sexual Medicine” Gray-scale ultrasound effectively detects erectile tissue fibrosis in young men with erectile dysfunction after using finasteride.
February 2018 in “The Journal of Sexual Medicine” Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.
66 citations
,
April 2017 in “International Journal of Andrology” Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
50 citations
,
March 2017 in “PeerJ” Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
22 citations
,
January 2018 in “European urology focus” New drugs and combination therapies are improving treatment for lower urinary tract symptoms.
10 citations
,
November 2014 in “Sexual medicine reviews” Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.
3 citations
,
February 2019 in “Molecular genetics and metabolism” The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.
12 citations
,
December 2013 in “The Journal of Urology” Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.
1 citations
,
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.
April 2024 in “International journal of impotence research” Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.
May 2015 in “Journal of The American Academy of Dermatology” Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.
1 citations
,
January 2015 in “Sexual Medicine Reviews” Current treatments for recurrent ischemic priapism are not well-defined and need more research.