110 citations
,
April 2020 in “Advances in Wound Care” Nanotechnology shows promise for better chronic wound healing but needs more research.
11 citations
,
May 2018 in “Frontiers in plant science” Arabidopsis PCaP2 helps plants survive drought by linking ABA and SA signals.
5 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
701 citations
,
August 2014 in “Nature medicine” Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
559 citations
,
October 2020 in “Frontiers in Molecular Biosciences” Solid lipid nanoparticles are promising for safe and effective drug delivery but need more research for clinical use.
527 citations
,
December 2011 in “Proceedings of the National Academy of Sciences” Dextran hydrogels improve burn wound healing and skin regeneration.
328 citations
,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
321 citations
,
December 2009 in “Journal of Dermatological Science” Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
280 citations
,
January 2004 in “The EMBO Journal” AGC2-1 protein is essential for root hair growth in Arabidopsis.
179 citations
,
November 2022 in “Frontiers in Plant Science” WRKY transcription factors help plants manage stress and support growth.
173 citations
,
August 2015 in “Developmental cell” The study identified unique genes in hair follicle cells and their environment, suggesting these genes help organize cells for hair growth.
169 citations
,
January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
161 citations
,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
156 citations
,
March 2022 in “Exploration” Bioactive inorganic particles-based biomaterials show promise for improving skin wound healing.
136 citations
,
September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
133 citations
,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
123 citations
,
January 2012 in “The Keio Journal of Medicine” Anti-angiogenic therapy can help treat cancer but may cause resistance and side effects, so alternative methods are being explored.
122 citations
,
December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
111 citations
,
April 2023 in “Ultrasonics Sonochemistry” Ultrasound helps efficiently extract beneficial compounds from maidenhairtree for potential medicinal use.
105 citations
,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
101 citations
,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
96 citations
,
March 2007 in “Developmental biology” The study found that the protein Dkk4 helps regulate hair growth by controlling Wnt signaling in mice.
90 citations
,
October 2023 in “Advanced Drug Delivery Reviews” Controlling inflammation can help heal diabetic foot ulcers.
86 citations
,
April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
81 citations
,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
79 citations
,
August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
78 citations
,
February 2024 in “ACS Omega” The scaffold is a promising material for wound healing and tissue engineering.
76 citations
,
January 2022 in “Journal of Tissue Engineering” Microneedle patches could replace injections but need more development for better use in medicine.
73 citations
,
November 2000 in “Proceedings of the National Academy of Sciences of the United States of America” There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
72 citations
,
June 2019 in “International Journal of Cosmetic Science” 18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.